Cmax


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maximum concentration

The peak concentration that a drug achieves in a specified compartment after the drug has been administrated and before administration of a second dose. Cmax is the opposite of Cmin—which is the minimum (or trough) concentration that a drug achieves after dosing.

Cmax

Pharmacology The peak serum concentration of a therapeutic drug. See Pharmaco-kinetics, Tmax. Cf Trough.

Cmax

Maximum concentration of a drug achieved after dosing.

Cmax

in pharmcokinetics, the maximum plasma concentration of the drug.
References in periodicals archive ?
The CMAX project required a custom environmental LCD enclosure to be housed in a large pylon, attached to a bus shelter.
Although grapefruit juice does not affect the disposition of IV midazolam, pretreatment with grapefruit juice was found to increase the AUC and Cmax of oral midazolam by 52% and 56%, respectively.
The Cmax for pimobendan tablet suspension was > 6 times higher than the Cmax for pimobendan powder suspension (8.
The Cmax rests above the ground when it's open, with a solid floor supported by 10 adjustable aluminum legs.
Administration of febuxostat (80 mg once daily) with indomethacin (50 mg twice daily) did not result in any significant changes in Cmax or AUC of febuxostat or indomethacin (less than 7%).
CMAX, has a total commitment to providing Phase I and II clinical trials on time and budget.
Cmax , tmax, were determined by plasma concentration time profiles and AUC0-8 was calculated by linear trapezoidal rule.
Noncompartmental pharmacokinetic analysis of total anthocyanins quantified as cyanidin-3-O-glucoside showed Cmax values of 2,321 and 1,138 ng/L at t max times of 2.
The changes in Cmax and AUC are non-significantly different in both healthy volunteers and tuberculosis patients, while significant variability was observed for the Tmax, which is higher in healthy volunteers compared to the tuberculosis patients.
First cars to use the platform will be the C-Max and Grand CMax, unveiled at the Frankfurt show last year and due in the showrooms this summer.
v = 0, the first node to be colored, C[] array to store the color assigned to nodes, vMax, the first node with highest assigned color and cMax, the highest assigned color.