clopidogrel

clopidogrel /clo·pid·o·grel/ (klo-pid´o-grel) a platelet inhibitor used as an antithrombotic for the prevention of myocardial infarction, stroke, and vascular death in patients with atherosclerosis; used as the bisulfate salt.

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clopidogrel,

a platelet aggregation inhibitor.

indications It is used to reduce the risk of stroke and myocardial infarction in high-risk patients.

contraindications Known hypersensitivity, active bleeding, and increased risk for bleeding (e.g., peptic ulcers) prohibits its use.

adverse effects Intracranial hemorrhage is a potential life-threatening side effect. Other adverse effects include rash, pruritus, nausea, vomiting, diarrhea, epistaxis, purpura, edema, hypertension, chest pain, headache, dizziness, musculoskeletal pain, upper respiratory tract infection, bronchitis, urinary tract infection, and hypercholesterolemia.

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clopidogrel

Plavix^® Cardiology An antiplatelet agent that ↓ the risk of ischemic stroke, MI, and vascular death in Pts with prior cardiovascular disease Contraindications Active bleeding–eg, PUD, intracranial hemorrhage, or Pts at risk for bleeding due to trauma, surgery or other drug therapy Adverse events Dyspepsia, purpura, diarrhea, rash, intracranial hemorrhage, neutropenia. See CAPRIE. Cf Aspirin.