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clofazimine

   Also found in: Wikipedia 0.01 sec.
clofazimine [klo-fa´zĭ-mēn]
an antibacterial effective against Mycobacterium species, including Mycobacterium leprae.

clofazimine
a human antileprosy drug used in the treatment of feline leprosy.

clofazimine
Lamprene® Therapeutics A lipophilic rhimophenazine used to manage leprosy and, with other drugs, atypical Mycobacterium infections–eg, MAC, discoid lupus, pyoderma gangrenosum Adverse effects GI upset, skin discoloration, rash


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The leprosy control program in Brazil distributes free dapsone, rifampin, and clofazimine as part of the World Health Organization multidrug regimen for treatment of leprosy.
Johns Hopkins scientists discovered that clofazimine interferes with a molecular pathway important in orchestrating the human body's immune response.
Failure to respond to sulfone or the occurrence of respiratory involvement or other complications requires the use of alternative therapy, such as rifampin in combination with clofazimine or ethionamide.
 
 
 
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