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clobetasol propionate

   Also found in: Wikipedia 0.01 sec.
clobetasol propionate
[klōbet′əsol prō′pyōnāt]
a topical corticosteroid antiinflammatory.
indications It is prescribed for the short-term treatment of inflammation and pruritus associated with certain moderate to severe types of dermatitis.
contraindications It is contraindicated for prolonged use, for applications to large areas of poor skin integrity, and with the use of occlusive dressing.
adverse effects Adverse reactions may include hyperglycemia, glycosuria, Cushing's syndrome, and suppression of hypothalamic-pituitary-adrenal functions. Because of the greater ratio of skin surface to body weight in children, they are at risk of absorbing a greater proportion of topical steroid.

clobetasol propionate (klōbā´tsol´ prō´pēnāt´),
n brand names: Dermovate, Temovate, Temovate Emollient Cream;
drug class: topical corticosteroid group I potency;
action: possesses antipruritic and antiinflammatory properties;
uses: psoriasis, exzema, contact dermatitis.


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For mild to moderate eczema, for example, a weak steroid such as hydrocortisone or desonide is used while more severe cases of eczema may use a higher potency steroid such as clobetasol propionate or fluocinonide.
Mild to moderate cases of eczema have been successfully treated with Desonide or Hydrocortisone, while the most severe cases call for the extremely potent steroid cream, Clobetasol Propionate.
A three-day audit of Sicor to determine its suitability as a manufacturer of clobetasol propionate and at least one other product ended without a 483 being issued, according to the just-released inspection report.
 
 
 
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