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the turning inside out of an organ, such as the urinary bladder.
exstrophy of the bladder congenital absence of a portion of the abdominal wall and bladder wall, the bladder appearing to be turned inside out, with the internal surface of its posterior wall showing through the opening in the anterior wall.
exstrophy of cloaca (cloacal exstrophy) a developmental anomaly in which two segments of bladder (hemibladders) are separated by an area of intestine with a mucosal surface, resembling a large red tumor in the midline of the lower abdomen.
congenital anomaly with two exstrophied bladder units separated by an exstrophied segment of intestine, which is usually cecum, receiving ileum superiorly and continuing distally to blind ending microcolon. A number of variants of anatomic disarray can occur.
Synonym(s): ectopia cloacae