Clear Cell Tumour

(redirected from Clear Cell Tumors)
A benign or malignant neoplasm composed of clear cells that may be of any embryologic (endo-, ecto-, meso-) or neuroectodermal origin; the cytoplasmic clearing may be real—lipid, mucopolysaccharide and mucosubstance—or artifactual, due to post-fixation shrinkage of cytoplasmic content away from an intact and more rigid cell membrane
Examples, clear cell tumours Balloon cell melanoma, signet ring cell carcinomas, renal cell, adrenal, ovary, parathyroid and thyroid carcinomas, clear cell tumours of tendons & aponeuroses, germ cell tumours—e.g., seminomas, dysgerminoma—histiocytosis X, lymphoma—B- and T- clear cell lymphomas—myeloma, clear cell type, myxoid lesions—benign and malignant—paraganglioma, and xanthoma. See Clear cell carcinoma
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Rather than metaplasia of the surface epithelium, endometrioid and clear cell tumors may result from retrograde menstruation, with the fallopian tube acting as a conduit for cells to gain access to the peritoneal cavity and the ovarian surface.
CD10 expression in epithelial tissues and tumors of the gynecologic tract: a useful marker in the diagnosis of mesonephric, trophoblastic, and clear cell tumors.
Jones, a research associate at the Johns Hopkins Kimmel Cancer Center, Baltimore, and associates evaluated 18,000 protein-encoding genes in ovarian clear cell tumors from eight patients (Science 2010 [doi:10.
For the study, the scientists evaluated mutations in 18,000 protein-encoding genes in ovarian clear cell tumors from eight patients at Johns Hopkins and from institutions in Taiwan and Japan.
pleomorphic adenoma, myoepithelioma, oncocytoma, mucoepidermoid carcinoma, and clear cell carcinoma) and metastatic clear cell tumors (e.
Glycogen-rich clear cell tumors and mucoepidermoid variants of SPC are uncommon.
Clear cell tumors (CCT) of the central nervous system (CNS) share similar morphologic features that have led to misdiagnosis in the past.
For patients with clear cell tumors, median OS and PFS were longer for temsirolimus than IFN, with hazard ratios of 0.
Clear cell adenocarcinoma is histologically and ultrastructurally similar to clear cell tumors of the female genital tract of possible mullerian origin.
The borderline tumors, in turn, appear to develop from the ovarian surface epithelium or from inclusion cysts in the case of serous and mucinous tumors and from endometriosis in the case of endometrioid and clear cell tumors.
The differential diagnosis of clear cell salivary neoplasias encompasses a broad range of possibilities, including primary salivary clear cell tumors, such as clear cell carcinoma (CCC), epithelial-myoepithelial carcinoma (EMEC), and clear cell myoepithelioma/myoepithelial carcinoma (CCMEC), as well as clear cell variants of other salivary tumors, including acinic cell carcinoma, oncocytoma, and mucoepidermoid carcinoma.
13) Accurate differential diagnosis with other clear cell tumors depends on an exhaustive search for intermediate cells and Alcian blue/PAS-positive mucin-producing cells.

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