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clavulanate

   Also found in: Wikipedia 0.01 sec.
clavulanate /clav·u·la·nate/ (klav´u-lah-nāt) a β-lactamase inhibitor used as the potassium salt in combination with penicillins in treating infections caused by β-lactamase–producing organisms.
clavulanate [klav´u-lah-nāt]
a β-lactamase inhibitor used as the potassium salt in combination with penicillins in treating infections caused by β-lactamase–producing organisms.

clavulanic acid, clavulanate
a beta-lactam product of Streptomyces spp. It binds irreversibly and inhibits β-lactamase produced by many organisms. Used commonly in combination with amoxicillin.


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The blends of clavulanate potassium were manufactured at a Glaxo plant located in the United Kingdom.
On the other hand, ampicillin-sulbactam, amoxicillin clavulanate, quinolones, macrolides, extended spectrum cephalosporins and tetracyclines seem effective for both of the microorganisms (Table 1) [39-55].
Clavulanate is not currently commercially available except in combination with beta-lactam antibiotics like amoxicillin.
 
 
 
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