Clara cell


Also found in: Dictionary, Thesaurus, Legal, Financial, Encyclopedia, Wikipedia.

Cla·ra cell

(klahr'ah),
a rounded, club-shaped, nonciliated cell protruding between ciliated cells in bronchiolar epithelium; believed to be secretory in function.

Clara cell

A cuboidal epithelial cell found in the lining of the terminal and the respiratory bronchioles of the lungs. Clara cells are nonciliated, and they secrete surfactant, like the type II alveolar epithelial cells found deeper in the bronchial tree.
See also: cell

Clara cell

(klăr′ă, klah′ră)
[Max Clara, Austrian anatomist, 1899–1937]
One of the secreting cells in the surface epithelium of the bronchioles. These cells, along with goblet cells, provide secretions for the respiratory tract. The secretion is a mucus-poor protein that coats the epithelium.

Clara,

Max, Austrian anatomist, 1899–.
Clara cell - a rounded, club-shaped, nonciliated cell protruding between ciliated cells in bronchiolar epithelium; believed to be secretory in function. Synonym(s): bronchiolar exocrine cell
Clara hematoxylin

Clara cell

nonciliated, secretory bronchiolar epithelial cells; function as stem cells for repair in the bronchioles and can divide into ciliated or nonciliated bronchiolar cells.
References in periodicals archive ?
for identity with the Clara cell protein and occurrence in
Clara cell secretory protein oxidation and expression in premature infants who develop bronchopulmonary dysplasia.
CCSP protein in distal airways of late control (E) and late BPA exposed (F) was expressed in cells resembling Clara cells (arrows).
104) The expression of Clara-cell differentiation antigens in NSCLC is unexpectedly low, (105) but the relevance of Clara cells as epithelial cell precursors in humans is not as clear as it appears in the mouse.
Neonatal Clara cell toxicity by 4-ipomeanol alters bronchiolar organization in adult rabbits.
Naphthalene cytotoxicity to differentiating Clara cells in neonatal mice.
Pulmonary heat shock protein expression after exposure to a metabolically activated Clara cell toxicant: relationship to protein adduct formation.
Arachidonic acid metabolism and regulation of ion transport in rabbit Clara cells.
Our results indicate that repeated exposure to chlorination by-products in the air of indoor swimming pools has an adverse effect on the Clara cell function in children, such that the anti-inflammatory role of CC16 in the lung could be diminished.
In the two crystalline silica-exposed groups, the MMP-9 expression increased after 7 days of exposure and was statistically significantly higher in the Clara cell-ablated group than in the group of mice with Clara cells after 14 days of exposure.
Determinants of Clara cell protein (CC16) concentrations in serum: a reassessment with two different immunoassays.