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Clara cell

   Also found in: Wikipedia 0.02 sec.
Clara cell
nonciliated, secretory bronchiolar epithelial cells; function as stem cells for repair in the bronchioles and can divide into ciliated or nonciliated bronchiolar cells.


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? Mentioned in ? References in periodicals archive
 
Bronchiolar epithelium cells known as Clara cells are thought to help defend airways against damage; Clara cell protein (CC16) is a lung-specific protein thought to protect the respiratory tract from inflammation.
Clara cell protein (CC16) is a small anti-inflammatory protein secreted by the nonciliated bronchiolar Clara cells.
For example, they secrete Clara cell secretory protein (CCSP) (9), which inhibits pulmonary inflammation (10); surfactant proteins, which prevent alveolar collapse (11-15); and protease inhibitors such as secretory leukocyte protease inhibitor (SLPI) (16-18) and elafin (17,18).
 
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