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cisapride

   Also found in: Wikipedia 0.02 sec.
cisapride (sis´prīd´),
n brand name: Propulsid;
drug class: oral prokinetic;
action: enhancement of acetylcholine release;
uses: symptomatic treatment and prophylaxis of nocturnal heartburn caused by gastroesophageal reflux disease.
cisapride
a substituted benzamide, similar to metoclopramide, which stimulates gastrointestinal motility. Used as an antiemetic by promoting gastric emptying.
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If safety concerns arise, the FDA may demand withdrawal of a drug from the market at any time (terfenadine {Seldane[R]}, cisapride {Propulsid[R]}, and cervistatin {Baycol[R]}, for example).
An overview of the drug development process by Tonkens, Ross / Physician Executive
Cisapride (Propulsid) was a highly effective motility medication, but it has recently been pulled from the market because it was found to cause serious heart rhythm changes.
Heartburn: How to Extinguish the Fire by Edison, Richard G. / Vibrant Life
The combination of the prokinetic medication cisapride and the antidepressants fluvoxamine and nefazodone is of particular concern.
Psychiatric manifestations of medications commonly prescribed in ... by Sataloff, Robert T. / Ear, Nose and Throat Journal
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