retinoic acid

(redirected from Cis-retinoic acid)
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retinoic acid

 [ret″ĭ-no´ik]
an oxidized derivative of retinol, believed to be the form of vitamin A that plays a role in the development and growth of bone and in the maintenance of normal epithelial structures. The all-trans isomer is called tretinoin and used as a keratolytic and antineoplastic agent. The 13-cis isomer is called isotretinoin and used as a treatment for acne.

ret·i·no·ic ac·id

(ret'i-nō'ik as'id),
Vitamin A1 acid; used topically to treat acne.
Synonym(s): vitamin A1 acid

retinoic acid

/ret·i·no·ic ac·id/ (ret″ĭ-no´ik) an oxidized derivative of retinol, believed to be the form of vitamin A that plays a role in the development and growth of bone and in the maintenance of normal epithelial structures. In pharmacology, it often denotes the all-trans isomer (tretinoin); the 13-cis isomer is usually called isotretinoin.

retinoic acid

(rĕt′n-ō′ĭk)
n.
1. A vitamin A derivative, C20H28O2, that serves as a regulator of morphogenesis and functions in the growth and development of bone and the maintenance of epithelium.
2. Either of two isomers of this compound, tretinoin or isotretinoin, that are used as drugs chiefly to treat acne. In both senses also called vitamin A acid.

(all-trans-)retinoic acid

Tretinoin The natural form of vitamin A, which transports monosaccharides in glycoprotein synthesis, as occurs in the turnover of mucosal epithelia of the oral cavity, respiratory and urinary tracts. See Retinal, Retinoic acid embryopathy, Tretinoin, Vitamin A.

ret·i·no·ic ac·id

(ret'i-nō'ik as'id)
Retinaldehyde in which the terminal -CHO has been oxidized to a -COOH; used topically in the treatment of acne; plays an important role in growth and differentiation.
Synonym(s): vitamin A1 acid.

Retinoic acid

Vitamin A1 acid which is used topically to treat acne.
Mentioned in: Warts

ret·i·no·ic ac·id

(ret'i-nō'ik as'id)
Agent used topically to treat acne.
Synonym(s): vitamin A1 acid.

retinoic acid

form of vitamin A, derived from retinal. See tretinoin.

Patient discussion about retinoic acid

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More discussions about retinoic acid
References in periodicals archive ?
June 14 /PRNewswire-FirstCall/ -- CuraGen Corporation and TopoTarget A/S (Copenhagen Stock Exchange: TOPO) announced today the initiation of patient dosing in a Phase I clinical trial evaluating the safety and tolerability of PXD101, a small molecule histone deacetylase (HDAC) inhibitor, in combination with cis-retinoic acid for the treatment of patients with advanced solid tumors.
When exisulind was combined with potential chemopreventive agents such as cis-retinoic acid or nordihydrogualarctic acid (NDGA) or chemotherapeutic agents such as cisplatin or paclitaxel (taxol), the researchers observed strong synergistic activity between exisulind and the other agents at concentrations that were subtherapeutic for each drug alone.