ciguatera

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ciguatera

 [se″gwah-ta´rah]
a form of fish poisoning, marked by gastrointestinal and neurologic symptoms due to ingestion of tropical or subtropical marine fish such as the barracuda, grouper, or snapper that have ciguatoxin in their tissues.

ci·gua·te·ra

(sē'gwă-tār'ă),
An acute toxic syndrome with predominantly gastrointestinal and neuromuscular features induced by ingestion of the flesh or viscera of various marine fish of the Caribbean and tropic Pacific reefs that contain ciguatoxin. The lipid-soluble, heat-stable toxin is produced by the dinoflagellate Gambierdiscus toxicus, which is epiphytic on red and brown algae. Herbivorous fish foraging on reef algae consume the flagellates and are in turn consumed by carnivorous fish, the toxin becoming increasingly concentrated as it passes up the food chain. Some 400 species of fish have been associated with human intoxication. Symptoms come on 3-12 hours after exposure and include vomiting and diarrhea, myalgia, dysesthesia and paraesthesia of the extremities and perioral region, pruritus, headache, weakness, and diaphoresis. Toxic effects usually resolve spontaneously in about 1 week.
[Sp. fr. cigua, sea snail]

ciguatera

/ci·gua·te·ra/ (se″gwah-ta´rah) a form of ichthyosarcotoxism, marked by gastrointestinal and neurologic symptoms due to ingestion of tropical or subtropical marine fish that have ciguatoxin in their tissues.

ciguatera

(sē′gwə-tĕr′ə)
n.
Poisoning caused by ingesting fish contaminated with ciguatoxin, characterized by gastrointestinal and neurological symptoms. Also called ciguatera fish poisoning, ciguatera poisoning.

ciguatera

[se′gwäta′rəh]
a form of fish poisoning, marked by GI and neurological symptoms, caused by ingestion of tropical or subtropical marine fish, such as the barracuda, grouper, or snapper that have accumulated ciguatoxin in their tissues. Ciguatoxin is heat resistant and is not detoxified by cooking. This form of poisoning is often misdiagnosed as multiple sclerosis.

ciguatera

poisoning by consumption of the flesh or viscera of sporadically toxic tropical predatory fish of a wide range of species. The causative heat-stable toxins (ciguatoxin, maitotoxin and others) originate in the dinoflagellate (Gambierdiscus toxicus) and possibly others or from associated bacterial microflora. The toxins are subject to bioaccumulation in fish which eat the dinoflagellates, and subsequently in the predators. Growth of the dinoflagellates is promoted by the destruction of their coral reef habitat. Poisoning characterized by vomiting, diarrhea and paresis in cats, dogs, humans. See also lyngbya.
References in periodicals archive ?
Warmer temperatures could also mean larger and longer blooms of harmful algae, including those that produce ciguatoxins.
KEY WORDS: ciguatera, ciguatera fish poisoning, ciguatoxins, incidence, poisoning, Puerto Rico, seafood.
The chemical structure of YTX is closely related to other ladder-shaped polyethers like ciguatoxin (CTXs), maitotoxin, brevetoxins (PbTXs), and some diarrhetic shellfish toxins (DSTs).
Although multidisciplinary research collaborations have improved our understanding of ciguatoxins and their transmission through the food chain (Dickey and Plakas 2010), few have resulted in proactive public health interventions for the PICTs.
Saxitoxins, brevetoxin and its derivatives, and ciguatoxin bind to different sites of voltage-dependant sodium channels, resulting in either an inhibition or a persistent activation of the channels, with consequent increase in intracellular calcium (Kao & Walkwe 1982, Gutierrez et al.
A solid-phase membrane immunobead assay with a monoclonal antibody directed against Pacific ciguatoxins and related polyether toxins was used to detect ciguatoxins or other antigenically related substances in fish tissues.
Likewise, each of these pathways may provide a means for potential therapeutic intervention of brevetoxin in neurotoxic shellfish poisoning and the more prolonged effects of related polyether ciguatoxin for ciguatera fish poisoning.
ciguatoxin [the toxin of ciguatera] or saxitoxin [the toxin of paralytic shellfish poisoning]), and cyanobacterial toxins (e.
Brevetoxins, along with the structurally and functionally related ciguatoxins, elicit these responses by activating voltage-gated sodium channels in nerve, heart, and muscle tissues (Wang and Wang 2002).
These lipid-soluble polyether toxins, like the ciguatoxins, exert their toxicity by activating voltage-sensitive sodium channels (1).
Purification and characterization of ciguatoxins from moray eel (Lycondontis javanicus, Muraenidae).
An unexpected difference between the developmental toxicity of both ciguatoxins and brevetoxins was that PbTx-1, but not CTX, caused cranial and optic deformities.