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ciguatera
(redirected from Ciguatoxins)

   Also found in: Wikipedia 0.07 sec.
ciguatera /ci·gua·te·ra/ (se?gwah-ta´rah) a form of ichthyosarcotoxism, marked by gastrointestinal and neurologic symptoms due to ingestion of tropical or subtropical marine fish that have ciguatoxin in their tissues.
ci·gua·ter·a (sgw-tr)
n.
Poisoning caused by ingesting fish contaminated with ciguatoxin, characterized by gastrointestinal and neurological symptoms such as diarrhea, vomiting, tingling, itchiness, and reversal of temperature perception.

ciguatera
poisoning by consumption of the flesh or viscera of sporadically toxic tropical predatory fish of a wide range of species. The causative heat-stable toxins (ciguatoxin, maitotoxin and others) originate in the dinoflagellate (Gambierdiscus toxicus) and possibly others or from associated bacterial microflora. The toxins are subject to bioaccumulation in fish which eat the dinoflagellates, and subsequently in the predators. Growth of the dinoflagellates is promoted by the destruction of their coral reef habitat. Poisoning characterized by vomiting, diarrhea and paresis in cats, dogs, humans. See also lyngbya.


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The causative toxins of its clinical manifestations are ciguatoxins (7).
This information on the association of brevetoxins with HDLs provides a new foundation for understanding the process by which the toxin is delivered to and removed from tissues and may permit more effective therapeutic measures to treat intoxication from brevetoxins and the related ciguatoxins.
Researchers at the University of Hawaii are studying another warm-water dinoflagellate (Gambierdiscus toxicus) that produces the ciguatoxins that cause ciguatera fish poisoning.
 
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