chymase

(redirected from Chymases)

chy·mo·sin

(kī'mō-sin),
An aspartic proteinase structurally homologous with pepsin, formed from prochymosin; the milk-curdling enzyme obtained from the glandular layer of the stomach of the calf. Acts on a single peptide bond (-Phe-Met-) in κ-casein.
Synonym(s): chymase, pexin, rennase, rennet, rennin

chymase

[kī′mās]
a serine protease present in human mast cells, most prominent in skin and connective tissue, where it can cleave angiotensin and stimulate mucous glands.

chymase

(kī′mās)
An enzyme in gastric juice that accelerates the action of the pancreatic enzymes.

chymase

see RENNIN.
References in periodicals archive ?
Mast cell tryptases and chymases in inflammation and host defense.
In the present study, we co-cultured myocardial microvascular endothelial cells (MMVECs) with MCs to study 1) whether MC granules (MCGs) can promote angiogenesis in MMVECs, 2) how tryptase and chymase play a role in modulating MC-induced neovessel maturation, and 3) whether co-culturing MMVECs with MCs leads to stimulation of Ang-Tie-2 signaling.
Tryptase and chymase enzyme activity in the MCG preparation was measured as described previously (17).
Tryptase and chymase are the predominant proteases present in MCGs.
Mast cell chymase and tryptase in abdominal aortic aneurysm formation.
Dipeptidyl peptidase I is essential for activation of mast cell chymases, but not tryptases, in mice.