Churg-Strauss syndrome


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Related to Churg-Strauss syndrome: sarcoidosis, polyarteritis nodosa, Wegener's granulomatosis, Goodpasture's syndrome, Microscopic polyangiitis

Churg-Strauss syndrome

 [cherg strous]
a form of systemic necrotizing vasculitis in which there is prominent lung involvement with severe asthma, eosinophilia, and granulomatous reactions. If present, skin lesions consist of tender subcutaneous nodules and bruiselike spots. Called also allergic granulomatosis, allergic granulomatous angiitis, and Churg-Strauss vasculitis.

Churg-·Strauss syn·drome

(chŭrg strows),
asthma, fever, eosinophilia, and varied symptoms and signs of vasculitis, primarily affecting small arteries, with vascular and extravascular granulomas.

Churg-Strauss syndrome

[churg′strous′]
Etymology: Jacob Churg, twentieth-century American pathologist; Lotte Strauss, twentieth-century American pathologist
a form of systemic necrotizing vasculitis in which there is prominent lung involvement with severe asthma, eosinophilia, and granulomatous reactions. If present, skin lesions consist of tender subcutaneous nodules and bruiselike spots. The cause is unknown. See also vasculitis.

Churg-Strauss syndrome

An autoimmune vasculitis of small to medium blood vessels with hypereosinophilia arising in a background of asthma and allergic rhinitis, which may be accompanied by tissue eosinophilia, peripheral neuropathy, gastrointestinal necrosis, cardiac lesions, and renal disease. Skin lesions are common in the form of purpura, erythema, urticaria and nodules arising on the scalp and/or extremities.

Churg-Strauss syndrome

Allergic granulomatosus & angiitis Internal medicine A small vessel vasculitis characterized by eosinophil-rich and granulomatous inflammation of the respiratory tract, formation of ANCA and necrotizing vasculitis of small-to-medium-sized vessels associated with asthma, edema. See Small vessel vasculitis, Systemic vasculitis.

Churg-Strauss syndrome

A rare form of blood vessel inflammation (vasculitis) that is almost invariably accompanied by severe ASTHMA. The cause is unknown and although the condition responds well to treatment with steroids or immunosuppressive drugs, the asthma usually persists. The syndrome is distinct from other vasculitides. There are suspicions that it may possibly be caused by certain drugs used to treat asthma, especially antileukotriene drugs.

Churg,

Jacob, Polish-born U.S. pathologist, 1910–.
Churg-Strauss syndrome - asthma, fever, eosinophilia, and varied symptoms and signs of vasculitis, primarily affecting small arteries, with vascular and extravascular granulomas. Synonym(s): allergic granulomatosis; allergic granulomatous angiitis; Strauss-Churg-Zak syndrome

Strauss,

Lotte, U.S. pathologist, 1913-1985.
Churg-Strauss syndrome - see under Churg
Strauss-Churg-Zak syndrome - Synonym(s): Churg-Strauss syndrome

Zak,

Frederick G., U.S. physician.
Strauss-Churg-Zak syndrome - Synonym(s): Churg-Strauss syndrome
References in periodicals archive ?
The American College of Rheumatology 1990 criteria for the classification of Churg-Strauss syndrome (allergic granulomatosis and angiitis).
A total of 47 possible, probable, or definite cases of Churg-Strauss syndrome and their 4,700 matched controls were identified and analyzed, Dr.
On multivariate analysis, the number of asthma drug classes used within the previous 6 months and the use of leukotriene modifiers in the previous 2-6 months were not associated with Churg-Strauss syndrome.
Antineutrophil cytoplasmic antibodies and the Churg-Strauss syndrome.
Presentation and outcome of gastrointestinal involvement in systemic necrotizing vasculitides: analysis of 62 patients with polyarteritis nodosa, microscopic polyangiitis, Wegener's granulomatosis, Churg-Strauss syndrome, or rheumatoid arthritis-associated vasculitis.
Churg-Strauss syndrome is a rare condition usually diagnosed on the basis of clinical criteria.
Allergic bronchopulmonary fungal disease (see above) can mimic Churg-Strauss syndrome because both occur in asthmatic patients and feature eosinophilic pneumonia along with granulomatous inflammation rich in eosinophils.
Although splenic lesions of Churg-Strauss syndrome have been described and consist of extravascular granulomas, eosinophilic abscess, and perivasculitis,[9] similar findings in the lymph nodes have not been likewise documented.
Systemic vasculitis with asthma and eosinophilia: a clinical approach to the Churg-Strauss syndrome.
Sarcoidosis, Wegener's granulomatosis, or Churg-Strauss syndrome
Churg-Strauss syndrome (CSS) is a rare form of small-vessel vasculitis with an incidence of 2.
Churg-Strauss syndrome in patients receiving montelukast as treatment for asthma.