Furthermore, at UEGW, data from a small double-blind, placebo-controlled, cross-over trial (GBR-7) to evaluate the effects of prucalopride in patients with chronic intestinal pseudo-obstruction
(CIP) due to visceral myopathy or neuropathy, were presented that demonstrated the favourable effect prucalopride had a on pain, nausea, vomiting, bloating and analgesic intake.
Four cases with chronic intestinal pseudo-obstruction due to hollow visceral myopathy.
Chronic intestinal pseudo-obstruction (CIPO) is a rare, severe syndrome with impaired gastro-intestinal motility leading to functional obstruction resembling mechanical obstruction.
The absence or reduction of ICC was seen in some gastrointestinal motility disorders, such as Hirschsprung's disease, chronic intestinal pseudo-obstruction
or slow transit constipation.
7,8] The absence or reduction of c-Kit-immunoreactive cells has been observed in a number of intestinal motility disorders, such as infantile hypertrophic pyloric stenosis, Hirschsprung disease, chronic intestinal pseudo-obstruction
, and slow-transit constipation.
R Our 15 year old daughter, who has Smith-Magenis syndrome and chronic intestinal pseudo-obstruction
, has had in-home caregiver-friends for the past five years.
These disorders include chronic intestinal pseudo-obstruction
, gastroesophageal reflux (GER), gastroesophageal reflux disease (GERD) and Hirschsprung's disease.