bacterial artificial chromosome

(redirected from Chromosomes, artificial, bacterial)
Also found in: Dictionary.

bacterial artificial chromosome

n. Abbr. BAC
A large DNA sequence that is artificially inserted into a bacterial genome for replication or expression.

bacterial artificial chromosome (BAC)

CLONING VECTOR based on the F PLASMID of ESCHERICHIA COLI, with the capacity to accept DNA inserts generally 100–300kb in size. Often used in the CLONE CONTIG SEQUENCING METHOD to obtain sequence CONTIGS in a genome sequencing project. See HUMAN GENOME PROJECT.