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The areas of HGT (the transformed components) in all 4 primary tumors showed significant chromosomal gains (median number of regions, 3; range, 1-6), but none showed chromosomal losses.
Leiomyosarcomas are most often associated with complex karyotypes with numerous chromosomal gains and losses; however, no consistent aberrations have been noted to date.
12) Furthermore, metanephric adenoma is typically immunoreactive for WT-1 and CD57, markers that were not expressed in our tumor, and chromosomal gains are not seen in metanephric adenoma.