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chromatin
(redirected from Chromatin structure)

   Also found in: Encyclopedia, Wikipedia 0.10 sec.
chromatin /chro·ma·tin/ (kro´mah-tin) the substance of chromosomes, the portion of the cell nucleus that stains with basic dyes. See euchromatin and heterochromatin.
sex chromatin  Barr body; the persistent mass of the inactivated X chromosome in cells of normal females.

chro·ma·tin (krm-tn)
n.
A complex of nucleic acids and proteins in the cell nucleus that stains readily with basic dyes and condenses to form chromosomes during cell division.

chromatin (krō´mtin),
n the genetic material present in the nucleus, consisting of DNA and associated proteins, seen as irregular clumps in quiescent cells.

chromatin
the substance of the chromosomes, composed of nucleic acids and basic proteins (histones), the material in the nucleus that stains with basic dyes.

sex chromatin
Barr body; the persistent mass of the material of the inactivated X chromosome in cells of normal females. See also drumstick.

chromatin Genetics The stainable material of interphase nuclei corresponding to chromosomes; chromatin consists of nucleic acids–DNA and associated histone protein, which are packed into nucleosomes; euchromatin is loosely packed and accessible to RNA polymerases. See Salt & pepper chromatin. Cf Heterochromatin.


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This modification alters chromatin structure to influence gene expression.
The scientists next disrupted the chromatin structure, dissociating the DNA from the histone H1.
This technique is important, as changes in chromatin structure play an important role in the silencing of certain genes in cancer, and histone deacetylase inhibitors have demonstrated anti-cancer effect.
 
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