chromatin

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Related to Chromatin structure: nucleosome

chromatin

 [kro´mah-tin]
the substance of the chromosomes, composed of DNA and basic proteins (histones), the material in the nucleus that stains with basic dyes.
sex chromatin the persistent mass of the material of the inactivated X chromosome in cells of normal females; called also Barr body.

chro·ma·tin

(krō'ma-tin),
The genetic material of the nucleus consisting of deoxyribonucleoprotein that occurs in two forms during the phase between mitotic divisions: as heterochromatin, seen as condensed, readily stainable clumps; as euchromatin, dispersed lightly staining or nonstaining material. During mitotic division the chromatin condenses into chromosomes.
[G. chrōma, color]

chromatin

/chro·ma·tin/ (kro´mah-tin) the substance of chromosomes, the portion of the cell nucleus that stains with basic dyes. See euchromatin and heterochromatin.
sex chromatin  Barr body; the persistent mass of the inactivated X chromosome in cells of normal females.

chromatin

(krō′mə-tĭn)
n.
A complex of nucleic acids and proteins, primarily histones, in the cell nucleus that stains readily with basic dyes and condenses to form chromosomes during cell division.

chro′ma·tin′ic adj.

chromatin

[krō′mətin]
Etymology: Gk, chroma, color
the material within a cell nucleus from which the chromosomes are formed. It consists of fine, threadlike strands of DNA attached to proteins called histones and is readily stained with basic dyes. Chromatin occurs in two forms, euchromatin and heterochromatin, which are distinguishable during the phases of the cell cycle by their different degrees of staining, which in turn depends how tightly they are coiled. During cell division, portions of the chromatin condense and coil to form the chromosomes. Also called chromoplasm, karyotin. See also chromatid, euchromatin, heterochromatin, sex chromatin. chromatinic, adj.
enlarge picture
Rim of chromatin outlining the nuclear membrane

chromatin

The threadlike stainable material seen in nuclei during interphase, which corresponds to chromosomes (nucleic acids/DNA, associated histones, and other proteins bundled into nucleosomes) in the eukaryotic nucleus.

chromatin

Genetics The stainable material of interphase nuclei corresponding to chromosomes; chromatin consists of nucleic acids–DNA and associated histone protein, which are packed into nucleosomes; euchromatin is loosely packed and accessible to RNA polymerases. See Salt & pepper chromatin. Cf Heterochromatin.

chro·ma·tin

(krō'mă-tin)
The genetic material of the nucleus, consisting of deoxyribonucleoprotein. During mitotic division, the chromatin condenses into chromosomes.
[G. chrōma, color]

chromatin

DNA. The elongated, fine-stranded complex of roughly equal quantities of DNA and the protein histone, from which chromosomes are made by condensing into a coil. The individual chromosomes cannot be distinguished in a chromatin strand.

chromatin

that part of the cell nucleus which becomes deeply stained with basic dyes. This is now known to be chromosomal material consisting of DNA together with HISTONE and nonhistone proteins.

chromatin

nuclear genetic material, which condenses (during cell division) into chromosomes

chro·ma·tin

(krō'mă-tin)
The genetic ma terial of the nucleus, consisting of deoxy ribonucleoprotein. During mitotic division, the chromatin condenses into chromosomes.
[G. chrōma, color]

chromatin (krō´mətin),

n the genetic material present in the nucleus, consisting of DNA and associated proteins, seen as irregular clumps in quiescent cells.

chromatin

the substance of the chromosomes, composed of nucleic acids and basic proteins (histones), the material in the nucleus that stains with basic dyes.

sex chromatin
Barr body; the persistent mass of the material of the inactivated X chromosome in cells of normal females. See also drumstick.
References in periodicals archive ?
These aberrant patterns are derived from different remodeling process between SCNT and fertilized embryos, which are caused by different chromatin structures of somatic and germ cells, respectively.
These proteins, including MeCP2, seem to directly regulate the condensation of chromatin structure and recruit HDACs and DNMTs, which may further enzymatically modify chromatin components (see figure 2) (Fuks et al.
These data suggest that epigenetic modifications involving HDACs result in a refinement of amygdaloid chromatin structure, which may be a contributing factor that alters the expression of genes implicated in alcohol tolerance and dependence (figures 4 and 5).
The significance of chromatin structure studies is more stressed owing to the greater awareness to transmission of genetic diseases because of higher incidence of gene imprinting defects, increased cancer frequency and other congenital and non-congenital defects in children conceived through assisted reproduction techniques.
As a method-positive control, GM00038B cells had relaxed chromatin structure after 4 J/[m.
1 PTMs found in histone “tails” (amino termini) such as acetylation, methylation and phosphorylation affect chromatin structure and exquisitely regulate gene expression.
647 "Manipulating Higher Order Chromatin Structure of the Beta-Globin Locus by Targeted Tethering of a 'looping' Factor" Oral Session: Thalassemia and Globin Gene Regulation: Regulation of Globin Gene Expression
Over the course of 17 chapters he covers basic radiation physics and chemistry; basic cell biology and molecular genetics; methods of cell and molecular radiology; ionizing radiation effects to the cytoplasm; damage to DNA by ionizing radiation; repair of radiation damage to DNA; cellular response to DNA damage; chromatin structure and radiation sensitivity; radiation- induced chromosome damage; modulation of radiation responses via signal transduction pathways; radiation-induced apoptosis; early and late responding genes induced by ionizing radiation; cell death, cell survival, and adaptation; bystander effects and genomic instability; tumor radiation biology; and radiation biology of nonmammalian species (three eukaryotes and a bacterium).
2000, Regulation of chromatin structure by site-specific histone H3 methyltransferases, Nature 406:593-599.
It is crucial to identify factors that regulate the chromatin structure since their alteration can lead to cancers, developmental abnormalities, and neurological disorders.
This will ultimately allow modulating asymmetry in vivo, providing unprecedented means to assess its impact on PRC2 function and chromatin structure.
Sperm Chromatin Structure Assay: The SCSA was performed as per the protocol described by Evenson et al.