prophase

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prophase

 [pro´fāz]
the first stage of cell replication in either meiosis or mitosis.

pro·phase

(prō'fāz),
The first stage of mitosis or meiosis, consisting of linear contraction and increase in thickness of the chromosomes (each composed of two chromatids) accompanied by migration of the two daughter centrioles and their asters toward the poles of the cell. In meiosis, prophase is complex and can be subdivided into stages: preleptotene, leptotene, zygotene, pachytene, diplotene, and diakinesis.
[G. prophasis, from prophainō, to foreshadow]

prophase

/pro·phase/ (-fāz) the first stage in cell reduplication in either meiosis or mitosis.

prophase

(prō′fāz′)
n.
1. The first stage of mitosis, during which the chromosomes condense and become visible, the nuclear membrane breaks down, and the spindle apparatus forms at opposite poles of the cell.
2. The first stage of meiosis, constituted by a series of events that include the thickening and coiling of the chromosomes, synapsis of homologous chromosomes, tetrad formation, and crossing over.

pro·pha′sic (-fā′zĭk) adj.

prophase

[prō′fāz]
Etymology: Gk, pro + phasis, appearance
the first of four stages of nuclear division in mitosis and in each of the two divisions of meiosis. In mitosis the chromosomes progressively shorten and thicken to form individually recognizable elongated double structures composed of two chromatids held together by a centromere. The nucleolus and nuclear membrane disappear, the spindle and polar bodies are formed, and the chromosomes begin to migrate toward the midplane of the developing spindle. In the first meiotic division, prophase is complex and subdivided into five stages: leptotene, zygotene, pachytene, diplotene, and diakinesis. In the second meiotic division the same processes occur as in mitotic prophase. See also anaphase, interphase, meiosis, metaphase, mitosis, telophase.
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Prophase

pro·phase

(prō'fāz)
The first stage of mitosis or meiosis, consisting of linear contraction and increase in thickness of the chromosomes (each composed of two chromatids) accompanied by migration of the two daughter centrioles and their asters toward the poles of the cell.
[G. prophasis, from prophainō, to foreshadow]

prophase

The first stage in cell division by MITOSIS and MEIOSIS, during which CHROMATIN coils up to form chromosomes.

prophase

the first stage of nuclear division (MITOSIS and MEIOSIS) in which the chromosomes coil and thicken and become visible with the optical microscope, condensing onto the inner wall of the NUCLEAR MEMBRANE. As the stage proceeds, the NUCLEOLUS disappears from view and the nuclear membrane disintegrates, leaving a clear area at the edge of the nucleus which contains the CENTROSOME.

Meiosis has a much more complicated prophase than mitosis, and can be summarized thus:

  1. (a) meiosis has two prophases, the first one complex (see below).the second rather similar to prophase in mitosis.
  2. (b) prophase 1 of meiosis can be divided into five substages: LEPTOTENE, ZYGOTENE, PACHYTENE, DIPLOTENE and DIAKINESIS. The essential processes occurring are: (i) pairing of homologous chromosomes, (ii) pairing of nonsister CHROMATIDS forming chiasmata with eventual CROSSING OVER.

prophase

the first stage of cell replication in either meiosis or mitosis.
References in periodicals archive ?
Tolerated and toxic doses led to separated mechanistic outcomes after 72 hr of exposure: a toxic dose led to cytotoxicity and chromatin condensation, whereas tolerated exposure resulted in continued FOS expression.
Therefore, we studied the effect OA at 40 [micro]M on various apoptotic parameters including apoptotic cell percentage through flow cytometric analysis, chromatin condensation using fluorescent imaging and expression of apoptotic proteins through western blot analysis.
19) Aniline blue stains lysine rich nucleoproteins, which is another sign of deterioration of chromatin condensation and was shown to correlate with AO staining.
1989, "Spermiogenesis in the Nile Tilapia Oreochromis niloticus with notes on a unique pattern of nuclear chromatin condensation," J.
Prophase cells exhibit a different form of chromatin condensation.
Likewise, the effect of vitamin E in the improvement of daily sperm production and amelioration of sperm chromatin condensation abnormality induced by sulfasalazine was superior to vitamin C.
s (NYSE:ENZ) Enzo Life Sciences division today announced the addition of a new apoptosis detection kit for monitoring chromatin condensation to its rapidly expanding CELLestial[TM] product line for live cell analysis.
Acidic Aniline Blue Staining (AABS): During histone replacement with protamines and chromatin condensation in spermatogenesis, normal sperm do not stain with aniline blue, but sperm with defective density or immature sperm absorb the stain (28).
Parasites incubated in the presence of compound (3) showed ultrastructural changes, such as the appearance of mitochondrial swelling with a reduction in the density of the mitochondrial matrix and the presence of vesicles inside the mitochondrion, indicating damage and significant change in this organelle; abnormal chromatin condensation, alterations in the nuclear envelope, intense atypical cytoplasmic vacuolization, and the appearance of autophagic vacuoles were also observed.
We observed a statistically significant decrease in AVTDs corresponding to chromatin condensation in cells of 5 subjects (subjects 301, 302, 406, 606, and 607; Table 2) of I0 at the frequency of 915 MHz (p < 0.
When subjected to agarose gel electrophoresis, this degraded DNA associated with chromatin condensation formed a DNA ladder, depicting multiples of 180-200 bp.
Effects of ethanol consumption on chromatin condensation and DNA integrity of epididymal spermatozoa in rat.