prophase

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prophase

 [pro´fāz]
the first stage of cell replication in either meiosis or mitosis.

pro·phase

(prō'fāz),
The first stage of mitosis or meiosis, consisting of linear contraction and increase in thickness of the chromosomes (each composed of two chromatids) accompanied by migration of the two daughter centrioles and their asters toward the poles of the cell. In meiosis, prophase is complex and can be subdivided into stages: preleptotene, leptotene, zygotene, pachytene, diplotene, and diakinesis.
[G. prophasis, from prophainō, to foreshadow]

prophase

/pro·phase/ (-fāz) the first stage in cell reduplication in either meiosis or mitosis.

prophase

(prō′fāz′)
n.
1. The first stage of mitosis, during which the chromosomes condense and become visible, the nuclear membrane breaks down, and the spindle apparatus forms at opposite poles of the cell.
2. The first stage of meiosis, constituted by a series of events that include the thickening and coiling of the chromosomes, synapsis of homologous chromosomes, tetrad formation, and crossing over.

pro·pha′sic (-fā′zĭk) adj.

prophase

[prō′fāz]
Etymology: Gk, pro + phasis, appearance
the first of four stages of nuclear division in mitosis and in each of the two divisions of meiosis. In mitosis the chromosomes progressively shorten and thicken to form individually recognizable elongated double structures composed of two chromatids held together by a centromere. The nucleolus and nuclear membrane disappear, the spindle and polar bodies are formed, and the chromosomes begin to migrate toward the midplane of the developing spindle. In the first meiotic division, prophase is complex and subdivided into five stages: leptotene, zygotene, pachytene, diplotene, and diakinesis. In the second meiotic division the same processes occur as in mitotic prophase. See also anaphase, interphase, meiosis, metaphase, mitosis, telophase.
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Prophase

pro·phase

(prō'fāz)
The first stage of mitosis or meiosis, consisting of linear contraction and increase in thickness of the chromosomes (each composed of two chromatids) accompanied by migration of the two daughter centrioles and their asters toward the poles of the cell.
[G. prophasis, from prophainō, to foreshadow]

prophase

The first stage in cell division by MITOSIS and MEIOSIS, during which CHROMATIN coils up to form chromosomes.

prophase

the first stage of nuclear division (MITOSIS and MEIOSIS) in which the chromosomes coil and thicken and become visible with the optical microscope, condensing onto the inner wall of the NUCLEAR MEMBRANE. As the stage proceeds, the NUCLEOLUS disappears from view and the nuclear membrane disintegrates, leaving a clear area at the edge of the nucleus which contains the CENTROSOME.

Meiosis has a much more complicated prophase than mitosis, and can be summarized thus:

  1. (a) meiosis has two prophases, the first one complex (see below).the second rather similar to prophase in mitosis.
  2. (b) prophase 1 of meiosis can be divided into five substages: LEPTOTENE, ZYGOTENE, PACHYTENE, DIPLOTENE and DIAKINESIS. The essential processes occurring are: (i) pairing of homologous chromosomes, (ii) pairing of nonsister CHROMATIDS forming chiasmata with eventual CROSSING OVER.

prophase

the first stage of cell replication in either meiosis or mitosis.
References in periodicals archive ?
Therefore, we studied the effect OA at 40 [micro]M on various apoptotic parameters including apoptotic cell percentage through flow cytometric analysis, chromatin condensation using fluorescent imaging and expression of apoptotic proteins through western blot analysis.
Necrosis-like PCD--No chromatin condensation, chromatin clustering to loose speckles
Potential applications for live-cell studies using the kit include monitoring the stages of chromatin condensation, rapid testing of compounds that induce apoptosis, and as a quick test to determine the health status of cells grown in culture.
Predictive value of sperm chromatin condensation (aniline blue staining) in the assessment of male fertility.
Further, most important findings of our study were that after I/R injury hepatocytes chromatin condensation were increased as compared to sham operated control rats.
Therefore this assay describes a relationship between semen quality and DNA damage because it incorporates a measure of chromatin condensation that in turn reflects the quality of processes controlling the differentiation and maturation of the spermatozoa.
They observed that in the area where microtubulescontact the perinuclear cistern, this collapses and the first chromatin condensations appear.
However, sperms of fish caught from the polluted sites showed variable deformations including: changes in head morphology, incomplete chromatin condensation, malformed middle piece, altered axonemal structure, wavy and sometimes ruptured plasma membrane, head-to-head and head-to-tail sperm agglutinations.
Thus, these biochemical changes are reflected in morphological changes in the cell and are marked by a series of reorganization characteristics such as chromatin condensation, loss of cell volume and membrane blebbing which are some of the most evident morphological changes of apoptotic cells (1.
Colleters of the outermost stipule show some cells with cytoplasm darkening, nuclear chromatin condensation, large vacuoles resulting from vacuole fusion, and a reduction in the number of organelles (Fig.
Most of these motifs are shared among many loci, suggesting that genomes are assembled like Lego blocks from a repertoire of more basic sequence elements, many of which do not encode proteins but other important functions such as transcription, translation, RNA processing, DNA replication, and chromatin condensation.