chromaffin cell

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Related to Chromaffin cells: adrenal medulla, Catecholamines, pheochromocytoma, Chromaffin granules, Enterochromaffin cells

chro·maf·fin cell

a cell that stains with chromic salts; found in adrenal medulla and paraganglia of the sympathetic nervous system.

chromaffin cell

any one of the special cells that compose the paraganglia and are connected to the ganglia of the celiac, renal, suprarenal, aortic, and hypogastric plexuses. The chromaffin cells of the adrenal medulla secrete two catecholamines, epinephrine and norepinephrine, which affect smooth muscle, cardiac muscle, and glands in the same way as sympathetic stimulation, by increasing and prolonging sympathetic effects.

chro·maf·fin cell

(krō-maf'in sel)
A cell that stains with chromic salts in medulla of the suprarenal gland and paraganglia of the sympathetic nervous system.

chromaffin cell

A cell that produces, stores, and secretes catecholamines (dopamine and norepinephrine). Chromaffin cells are found in the medulla of the adrenal glands and in small clusters in the sympathetic ganglia.
See also: cell
References in periodicals archive ?
Cg A, isolated from chromaffin cells of the adrenal medulla, is an acidic glycoprotein with 439 amino acids (21) and is present in secretory dense core granules located within the cytoplasm of these NE cells (22), However, CgA production seems to depend on tumor type or tumor differentiation and the sensitivity of CgA detection in tissue or plasma may be low in moderately or poorly differentiated NE carcinomas (23).
In the second stage, beginning 48 hours after the injury, the adrenals are greatly enlarged but regain their lipoid granules, while the medullary chromaffin cells show vacuolization; the edema begins to disappear, numerous basophiles appear in the pituitary; the thyroid shows a tendency towards hyperplasia (more marked in the guinea pig); general body growth ceases, and the gonads become atrophic; in lactating animals, milk secretion stops.
To evaluate the cytotoxic effect in cultured chromaffin cells, LDH release assay has been used by (Sicard et al.
A primary response is the activation of brain centers, which eventually results in the release of cortisol from the steroid-producing cells and of catecholamines from the head kidney chromaffin cells.
Phaeochromocytoma is a catecholamine-secreting, neuroendocrine tumour arising from chromaffin cells.
Amperometric recordings in chromaffin cells from mice exposed to 68 mg (140 [micro]mol)/kg bw BDE-47 did not reveal changes in catecholamine release parameters.
The cells, called chromaffin cells, have large vesicles, 200 nanometers (nm) across.
These cell stain yellow brown with the chrome salts and hence are called chromaffin cells.
Malignancy is normally determined by evidence of infiltration of surrounding tissues or by the spread of disease to distant sites, particularly those where chromaffin cells are not usually found (eg, lymph nodes, bone).
The hypothesis is that bovine adrenal chromaffin cells express multiple subtypes that can be identified using receptor protection assays.
Pheochromocytoma arises from chromaffin cells and usually develops in the adrenal medulla.
True (A) or false (B)--click on the correct answer: approximately 85% of phaeochromocytomas arise from chromaffin cells in the adrenal medulla.