chromaffin cell

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chro·maf·fin cell

a cell that stains with chromic salts; found in adrenal medulla and paraganglia of the sympathetic nervous system.

chromaffin cell

any one of the special cells that compose the paraganglia and are connected to the ganglia of the celiac, renal, suprarenal, aortic, and hypogastric plexuses. The chromaffin cells of the adrenal medulla secrete two catecholamines, epinephrine and norepinephrine, which affect smooth muscle, cardiac muscle, and glands in the same way as sympathetic stimulation, by increasing and prolonging sympathetic effects.

chro·maf·fin cell

(krō-maf'in sel)
A cell that stains with chromic salts in medulla of the suprarenal gland and paraganglia of the sympathetic nervous system.

chromaffin cell

A cell that produces, stores, and secretes catecholamines (dopamine and norepinephrine). Chromaffin cells are found in the medulla of the adrenal glands and in small clusters in the sympathetic ganglia.
See also: cell
References in periodicals archive ?
evoked catecholamine release using carbon fiber microelectrode amperometry from isolated chromaffin cells and PC12 cells as described previously (Westerink and Vijverberg 2002).
For experiments, four to eight million chromaffin cells are gravity fed onto the glass fiber filter located in the filter holder and superfused with temperature controlled BSS at a flow rate of 1.
Lozorthes Y, Bes JC, Sagen J, Tafani M et al, "Transplantation of Human Chromaffin Cells for Control of Intractable Cancer Pain", Acta Neurochir.
SCG10 is expressed also in mature chromaffin cells and PC12 cells at low level and is inducible by NGF |20, 27~.
21-25) The local availability of steroids in the anatomical surroundings of the adrenal cortex allow the adrenal medulla chromaffin cells to be exposed to very high concentration of glucocorticoids (more than 100-fold its concentration in the systemic circulation) that will induce PNMT synthesis and hence epinephrine production.
Lack of COMT in sympathetic nerves, where most norepinephrine is initially metabolized, means that the metanephrines are relatively specific markers for catecholamines produced in chromaffin cells and their tumor derivatives.
PC12 cells as a model to study the effects of opiods on normal and tumoral adrenal chromaffin cells.
While MEN 2-related pheochromocytomas shared many of the characteristics of normal adrenal medullary chromaffin cells, those seen in VHL disease did not.
DISCUSSION: Pheochromocytomas are tumors that arising from chromaffin cells of the adrenal medulla.
PCC and paraganglioma (PGL) are rare neuroendocrine tumors arising from chromaffin cells.