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Therefore, to elucidate potential sites of action of cholinergic agents which are known to inhibit myopia, it is essential to investigate the regulation of the cholinergic system in the retina, choroid and sclera during normal and myopic eye development.
This maintains excitable cells in a depolarized state, in which they behave like cholinergic agents and cause dose-dependent hypotension, bradycardia and respiratory-rate depression (3).