cholesteryl ester transfer protein

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cholesteryl ester transfer protein (CETP)

a plasma glycoprotein that plays a role in the movement of cholesterol from the peripheral tissue to the liver by mediating the transfer of cholesteryl esters from HDL cholesterol to apolipoprotein B-containing proteins, which are then metabolized to lipoproteins that are removed from the circulation by receptors in the liver. Deficiency of this protein, an autosomal-dominant trait, results in markedly higher plasma levels of HDL cholesterol and apolipoprotein A-I. Also called lipid transfer p. I.

cholesteryl ester transfer protein

Abbreviation: CETP
A protein that circulates in plasma and facilitates the chemical transfer of cholesteryl esters from high-density lipoproteins to other lipoproteins.
See also: protein
References in periodicals archive ?
Increased high-density lipoprotein levels caused by a common cholesterylester transfer protein gene mutation.
Therefore, determining that other inhibitors of cholesterylester transfer protein (CETP), or medications in the same class as torcetrapib without potential RAAS toxicity may, be efficacious.