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vinyl chloride |
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vinyl /vi·nyl/ (vi´nil) the univalent group CH2dbondCH—. vinyl chloride a vinyl group to which an atom of chlorine is attached; the monomer which polymerizes to polyvinyl chloride; it is toxic and carcinogenic.
vinyl chloride Toxicology A monomer that polymerizes to polyvinyl chloride–PVC, which is used in organic chemistry and manufacturing plastics Adverse effects VC is carcinogenic and carries a risk of liver, brain, lung CA,
lymphoma, leukemia. See PVC–polyvinyl chloride. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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2002) to chloroethylene oxide and chloracetaldehyde, metabolites that can react with DNA bases and promote mutations in bacterial and mammalian cells (Marion and Boivin-Angele 1999; Marion et al. Chloroethylene mixtures: pharmacokinetic modeling and in vitro metabolism of vinyl chloride, trichloroethylene, and trans-1,2-dichloroethylene in rat. First, the form of the metric (total daily metabolism divided by the volume of the liver) was consistent with the mode of action for the end point of concern (liver tumors), which involves DNA adduct formation by a highly reactive chloroethylene epoxide produced from the metabolism of vinyl chloride. |
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