chloroacetic acid

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Related to Chloroacetate: Chloroacetic acid, ethyl chloroacetate

chlor·o·a·ce·tic ac·id

(klōr'ō-ă-sē'tik as'id),
An acetic acid in which one or more of the hydrogen atoms are replaced by chlorine. According to the number of atoms so displaced, the acid is called monochloroacetic (chloroacetic), dichloroacetic, or trichloroacetic.
Synonym(s): chloracetic acid
References in periodicals archive ?
The sonolytic degradation of 4-nitrophenol was monitored identically under the same conditions as the hydrolysis of 4-nitrophenyl chloroacetate.
Histochemical staining for chloroacetate esterase (Leder stain), which stains neutrophils and precursors, is usually positive, although sometimes only focally.
Myeloblasts (but not erythroblasts) are usually positive for myeloperoxidase (MPO), Sudan Black B, and, often, chloroacetate esterase.
Cytochemical staining (Leder stain) showed the blasts were positive for chloroacetate esterase, whereas the crystals were negative for myeloperoxidase and chloroacetate esterase.
The original diagnostic BM aspirate smears and subsequent peripheral blood smears were Wright stained and stained for the presence of the following: myeloperoxidase (MPO), Sudan Black B (SBB), chloroacetate esterase (CAE), [Alpha]-naphthyl acetate esterase (ANAE), and [Alpha]-naphthyl-butyrate esterase (ANBE).
The BM aspirate smears and touch preparations of the BM core biopsy had been routinely stained with Wright stain and for the presence of MPO, Sudan black B, [Alpha]-naphthyl acetate esterase, [Alpha]-naphthyl butyrate esterase, and chloroacetate esterase (Sigma Chemical Co, St Louis, Mo) according to kit procedures.
The blasts showed coarse granular staining for periodic acid-Schiff, but failed to stain with Sudan black B and chloroacetate esterase.