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mechlorethamine |
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mechlorethamine /mech·lor·eth·amine/ (mek″lor-eth´ah-mēn) one of the nitrogen mustards, used in the form of the hydrochloride salt as an antineoplastic, particularly in disseminated Hodgkin's disease.
mechlorethamine [mek″lor-eth´ah-mēn] an alkylating agent that produces interstrand and intrastrand cross-linkages in DNA with resultant miscoding, breakage, and failure of replication. Used primarily for the treatment of disseminated hodgkin's disease, especially in the MOPP treatment regimen, and for other lymphomas, including mycosis fungoides; administered intravenously as the hydrochloride salt. Called also nitrogen mustard.
mechlorethamine
mechlorethamine Oncology An alkylating nitrogen mustard chemotherapeutic used for lymphomas Adverse effects GI Sx, BM suppression, skin vesiculation at injection site. See MOPP regimen. Want to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit the webmaster's page for free fun content. |
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