chlorhexidine

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chlorhexidine

 [klor-hek´sĭ-dēn]
an antibacterial compound used in antimicrobial skin cleansers for surgical scrub, preoperative skin preparation, and cleansing skin wounds.

chlorhexidine

/chlor·hex·i·dine/ (klor-heks´ĭ-dēn) an antibacterial effective against a wide variety of gram-negative and gram-positive organisms; used also as the acetate ester, as a preservative for eyedrops, and as the gluconate or hydrochloride salt, as a topical anti-infective.

chlorhexidine

[-hek′sidēn]
an antimicrobial agent used as a surgical scrub, hand rinse, and topical antiseptic. It is effective against gram-positive organisms, gram-negative organisms, aerobes, facultative anaerobes, and yeast.

chlorhexidine

A disinfectant agent widely used in surgery for preoperative skin cleansing and for sterilizing instruments by soakage. The drug is on the WHO official list. A brand name is Hibitane.

chlorhexidine

; Savlon; Hydrex 0.05% chlorhexidine (acetate or gluconate) in industrial methylated spirit (IMS) or water; powerful topical antiseptic effective against a wide range of skin flora, but non-effective against mycobacteria, Pseudomonas or spore forms; incompatible with soap; used for skin cleansing (allow to evaporate to dry for 5 minutes after application); 4% chlorhexidine gluconate in solution (Hibitane) is used as a preoperative surgical scrub

antiseptic 

An agent that kills or prevents the growth of bacteria. This term is generally restricted to agents that are sufficiently non-toxic for superficial application to living tissues. These include the preservatives for eye drops and contact lens solutions. Examples of antiseptics are alcohol, benzalkonium chloride, cetrimide, chlorbutanol, chlorhexidine, hydrogen peroxide, thimerosal (or thiomersalate). Other agents that are too toxic to be applied to living tissues are called disinfectants and are used to sterilize instruments and apparatus. See disinfection; ethylenediamine tetraacetic acid; neutralization; sterilization.

chlor·hex·i·dine

(klōr-heksi-dēn)
A bis-biguanide useful as a topical antiseptic. The gluconate form is used as an oral rinse to inhibit oral bacteria in some conditions.

chlorhexidine (CHX) gluconate,

n brand names: Peridex, PerioGard;
drug class: antiinfective oral rinse;
action: absorbed by tooth surfaces, dental plaque, and oral mucosa; sustained reduction of plaque organisms;
uses: as a rinse as a part of treatment of periodontal disease, irrigation during periodontal procedures, and possibly as an aseptic prerinse before dental procedures.

chlorhexidine

a bisbiguanide antiseptic with antibacterial, antifungal and some antiviral activity; used in skin cleansers for surgical scrub, preoperative skin preparation, cleansing skin wounds and teat dips. Used as the acetate, gluconate or hydrochloride salts. Proprietary names are Hibitane, Nolvasan.

chlorhexidine digluconate
used as a sclerosing agent for chemical vasectomy in dogs.
chlorhexidine teat dip
0.5 to 1.0% chlorhexidine in polyvinylpyrrolidone or as 0.3% solution in water.
References in periodicals archive ?
Keywords: Povidone-iodine, Chlorhexidine gluconate scrubs, Surgical site infections.
A post hoc Tukey's test revealed no significant difference between chlorhexidine gluconate and 0.
12% chlorhexidine gluconate (Peridex[R]; 3 M ESPE, Minneapolis, Minn) and essential oils and methyl salicylate (Listerine[R]; McNeil-PPC, Inc, Skillman, NJ), both anti-plaque and anti-gingivitis mouth rinses approved by the Council on Dental Therapeutics of the American Dental Association (ADA), do not have a negative effect on the oral microbial flora.
In this case the reduction in infection rates could be due to alcohol alone, rather than the independent variable of 2% chlorhexidine gluconate with 70% isopropyl alcohol.
5% in patients patch tested with chlorhexidine gluconate 1% at a Danish skin clinic (61).
Evidence for Using Chlorhexidine Gluconate Preoperative Cleansing to Reduce Risk of Surgical Site Infection.
Igarashi Y, Suzuki J 1985 Cochlear ototoxicity of chlorhexidine gluconate in cats Archives of Otorhinolaiyngology 242 (2) 167-76
Many of the lotions on the market for healthcare workers provide label information about compatibility with latex gloves and antimicrobial ingredients, such as chlorhexidine gluconate.
This persistence is due to chlorhexidine gluconate binding to the protein of the skin and, thus, being available for residual activity over a relatively long period of time.
Sage[R] 2% Chlorhexidine Gluconate Cloths -- Patient Preoperative Skin Preparation - contains 500mg of rinse-free 2% CHG solution per cloth for rapid, broad spectrum skin antisepsis with persistent activity.
Tenders are invited for Containing Chlorhexidine Gluconate 0.
This purchasing contract covers products including Tegaderm CHG Chlorhexidine Gluconate I.