A carcinogenic chlorinated polycyclic ketone insecticide and fungicide used in the US between 1966 and 1975. It gained notoriety from its improper handling and dumping into the James River, Virginia, which was subsequently closed to fishing. Chlordecone has a 30-year environmental half-life
Toxicity Tremors, nystagmus, memory loss, headaches, slurred speech, unsteadiness, incoordination, loss of weight, rash, hepatomegaly, decreased libido, sterility, chest pain, arthralgia, and the increased risk of cancer
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Two additional studies have shown statistically significant positive associations of other OC insecticides, including chlordecone, [beta]-hexachlorocyclohexane (HCH), and [gamma]-HCH with prostate cancer (Kumar et al.
This contract involves the taking of food, sample preparation and research of chlordecone in food samples.
However, this study is in variance with other works [12,17] that reported an increase in WBC when chlordecone was administered to male Sprague-Dawley rats [17] and when arsenic-poisoned cattle blood parameters were evaluated.
Washington, June 23 (ANI): Researchers have found that exposure to chlordecone (also named Kepone), an organochlorine chemical, can increase the risk of prostate cancer.
The money will help fund a plan that calls for stricter limits on the amount of chlordecone used on crops and better-equipped laboratories to test for presence of the pesticide.
Until 2002, many plantations continued to spray a pesticide called chlordecone to control weevils, even though the French government banned the chemical in 1993.
They show that ministers this week (Tues) ordered that aldrin, chlordane, dieldrin, endrin, heptachlor, hexachlorobenzene, mirex, toxaphene, polychlorinated biphenyls (PCB), DDT, chlordecone, the sum of alpha, beta- and gamma-HCH, and hexabromobiphenyl be present in wastes at concentrations not exceeding 50 mg/kg.
Cholestyramine has been used as a treatment for intrahepatic cholestasis of pregnancy and as an antidote for some types of diarrhea, chlordecone pesticide poisoning, and digitalis toxicity.
Eric Sobel, a University of Florida rheumatologist, exposed lab mice to chlordecone (a pesticide in ant and roach traps).
Since then, signatory nations have added four more POPs to the list: the pesticides lindane (also known as gamma-hexachlorocyl-cohexane) and chlordecone (also known as kepone); hexabromobiphenyl, a polybrominated flame retardant; and polycyclic-aromatic hydrocarbons (PAHs), which are combustion byproducts.
Besides the chemicals listed in the text, other PBTs of concern include the pesticides chlordecone, isodrin, methoxychlor, pendimethalin, tributyl tin, and trifiuralin; the industrial chemicals benzo[a]pyrene, benzo(g,h,i)perylene, hexabromobiphenyl, pentachlorobenzene, and tetrabromobisphenol-A; the industrial byproduct octachlorostyrene; cadmium and its compounds; polybrominated flame retardants; phthalates; and chlorinated solvents.
Table 1 List of the Sixteen Substances Initially Included in the CLRTAP POPs Protocol Annex Pesticides Industrial Unintentional chemicals by-products I Aldrin Hexabromobiphenyl Chlordane PCBs Chlordecone DDT Dieldrin Endrin Heptachlor Hexachlorobenzene Mirex Toxaphene II HCH/Lindane DDT PCBs III Dioxins Furans Hexachlorobenzene PAHs Source: Adapted from Annex I-III of the protocol.