Chlamydophila

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Chlamydophila

(kla-mid-ō-fil'ă),
A bacterial genus with a complex obligatory intracellular life cycle; the infective form is the elementary body that penetrates the host cell, replicating as the rediculate body by binary fission; replication occurs in a vacuole called the inclusion body; lacking peptidoglycan in cell walls. Conditions associated with Chlamydophila include pneumonitis in cattle, sheep, swine, cats, goats, and horses; bovine sporadic encephalomyelitis, enteritis of calves; (C. pneumoniae, C. pecorum subtypes); enzootic abortion of ewes (C. abortus); also affecting cats (C. felis); guinea pigs (C. caviae), and C. psittaci, the agent of psittacosis/ornithosis in psittacine and nonpsittacine birds.

Chla·myd·o·phil·a

(kla-mid-ō-fil'ă, klă-midō-filă)
A newly named genus in the family Chlamydiaceae, including species formerly assigned to the genus Chlamydia.

Chlamydophila

(kla-mi-dof'i-la) [Gr. chlamys, cloak + ?]
A bacterial genus of intracellular parasites of the family Chlamydiaceae, comprising six species, of which C. pneumoniae and C. psittaci infect humans. The organisms are characterized as bacteria because of the composition of their cell walls and their reproduction by binary fission, but they reproduce only within cells. These species cause a variety of diseases. See: Chlamydia

Chlamydophila pneumoniae

A species of Chlamydophila that is an important cause of pneumonia, bronchitis, and sinusitis. It is believed to be transmitted from person to person by respiratory tract secretions (e.g., by airborne droplets). Most cases are mild and rarely require hospitalization. It is possible that this organism is a factor in the development of coronary artery disease.

Treatment

Treatment consists of daily tetracycline, macrolide, or fluoroquinolone for 14 to 21 days.

Chlamydophila psittaci

A species of Chlamydophila common in birds and animals. Pet owners, pet shop employees, poultry workers, and workers in meat-processing plants are frequently exposed to C. psittaci.

Symptoms

After an incubation period of 5 to 15 days, nonspecific symptoms (e.g., malaise, headache, fever) develop; progression to pneumonia is serious and may be fatal. Alternatively, the disease may resemble infectious mononucleosis with fever, pharyngitis, hepatosplenomegaly, and adenopathy. Severity may vary from inapparent to mild to fatal systemic disease.

Prognosis

The fatality rate is approx. 20% in untreated patients.

Treatment

Treatment consists of tetracycline or doxycycline for 10 to 21 days.

Chlamydophila

a genus of obligately intracellular bacteria in the family Chlamydiaceae. Members were previously in the genus Chlamydia.

Chlamydophila abortus
causes enzootic abortion of ewes. Previously called Chlamydia psittaci.
Chlamydophila caviae
causes conjunctivitis in guinea pigs. Previously called Chlamydia psittaci.
Chlamydophila felis
cause of upper respiratory tract disease, principally involving conjunctivitis, in cats. Also recovered from the reproductive tract, where its pathogenic significance is uncertain. Previously called Chlamydia psittaci.
Chlamydophila pecorum
causes sporadic bovine encephalomyelitis, but also associated with enteritis, polyarthritis, pneumonia and conjunctivitis in ruminants, and reproductive tract disease in koalas. Previously classified as Chlamydia psittaci and C. pecorum. Conjunctivitis in sheep previously attributed to Colesiota conjunctivae.
Chlamydophila pneumoniae
different biovars infect horses, koalas and humans. Pathogenic significance in koalas and horses is uncertain, but in humans it is a significant cause of pneumonia. Previously classified as Chlamydia psittaci and C. pneumoniae.
Chlamydophila psittaci
cause of psittacosis and ornithosis, systemic disease of psittacine and other avian species, including domestic poultry. Zoonotic. Previously called Chlamydia psittaci.
References in periodicals archive ?
trachomatis (strains D/ UW-3/CX [18] and A/Har-13 [19]), Chlamydia muridarum (rodent strain MoPn [20]), Chlamydophila pneumoniae (human strains AR39 [20]; CWL029 [21], and J138 [21]), and Chlamydophila caviae (guinea pig inclusion conjunctivitis strain [22]), the most distantly related species of Chlamydiaceae.
Genome sequence of Chlamydophila caviae (Chlamydia psittaci GPIC): examining the role of niche-specific genes in the evolution of the Chlamydiaceae.
A/Har-13; Chlamydophila caviae, strain GPIC; Chlamydia muridanum, strain Nigg; Chlamydophila abortus, strain S26/3; and another seed stock of A/SA-1 were included for PCR amplification analyses (see Preparation of Genomic DNA and Sequencing of ompA and 16S rRNA for Each Clone).