Chinese Hamster Ovary Cell

(redirected from Chinese hamster ovary)
Also found in: Acronyms.
A line of fibroblasts isolated in 1958, which is used in research, grows well in culture, and spontaneously transforms to a malignant morphology, due to cytoskeletal disorganization
References in periodicals archive ?
The Chinese hamster ovary (CHO) cells were kindly supplied by Professor Salvadori (UNESP-Botucatu.
A cloned recombinant Chinese hamster ovary cell line (CHO-EPO) manipulated to secrete recombinant human erythropoietin was used in this work.
The most effective production of pharmaceutically active glycoproteins is using mammalian expression systems like Chinese hamster ovary cells (CHO), mouse fibroblast cells (C127-BPV) and transgenic animals expressing the cDNA or genomic DNA encoding the protein of interest (5,24).
The drugs, aphidicolin and ara-c, were tested on four Chinese Hamster Ovary (CHO) cell lines to discover if they would cause apoptotic effects on the cells.
To find a replacement signaler that would start the chain reaction, the researchers engineered Chinese hamster ovary cells to have human insulin receptors.
The FDA placed a clinical hold on IB1001 in July 2012 when a number of study subjects developed antibodies to the host cell protein, Chinese Hamster Ovary cell proteins (CHOP), of IB1001.
Mammalian expression systems are mostly developed using Chinese Hamster Ovary (CHO) cells and HEK-293 (Human Embryonic Kidney) cells.
continuous cell lines such as Chinese hamster ovary (CHO) and myeloma cells (NSO and SP2/0)
AutovaxID is suitable for growing antibody-secreting cell lines, including hybridomas and Chinese hamster ovary (CHO) cells which are currently the back bone of commercial therapeutic protein manufacture.
Another study by Liu and Huang (1996) demonstrated that calcium ions are accumulated in the nuclei of Chinese hamster ovary (CHO)-K1 cells after arsenite treatment.
Generation of Chinese Hamster Ovary Cells Stably Overexpressing Proprotein Convertase 7.
The expression and large-scale production of rhTSH in Chinese hamster ovary (CHO) cells have been reported (2, 3), and clinical trials for its proposed diagnostic use to stimulate radioiodine uptake into residual or metastatic thyroid tissue in patients with thyroid carcinoma are underway (4).

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