Chili Pepper

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Related to Chile peppers: hot pepper

capsicum

(kap-si-kum) ,

Capzasin-HP

(trade name),

Zostrix

(trade name),

capsaicin

(trade name),

chili pepper

(trade name),

African bird pepper

(trade name),

Capsicum annuum

(trade name)

Classification

Therapeutic: analgesics
Oral: Dyspepsia Topical: Arthritis, lower back pain, and neuralgias Intranasal: Headache, perennial rhinitis

Action

Binds to nociceptors in the skin, causing neuronal excitation, heightened sensitivity and cutaneous vasodilation. Initially, a burning or pricking sensation is produced. With repeated use, a period of desensitization occurs caused by substance P depletion.

Therapeutic effects

Decreased pain sensation.

Pharmacokinetics

Absorption: Well absorbed when applied to skin.
Distribution: Unknown.
Metabolism and Excretion: Metabolized by the cytochrome P450 system to active metabolites.
Half-life: 1.6 hrs (topical).

Time/action profile

ROUTEONSETPEAKDURATION
POUnknownUnknownUnknown
TopicalUnknownUnknownUnknown

Contraindications/Precautions

Contraindicated in: Hypersensitivity or allergy; Injured skin or open wounds (topical); Infectious or inflammatory GI conditions (oral); Obstetric: Pregnancy and lactation (oral).
Use Cautiously in: Obstetric: Pregnancy and lactation (topical); Pediatric: Safety and efficacy has not been shown in children; Kidney and/or liver disease (long-term, high doses); Surgery (discontinue use 2 wk prior to procedure).

Adverse Reactions/Side Effects

Dermatologic

  • burning (topical)
  • erythema (topical)
  • urticaria (topical)
  • flushing
  • sweating

Ear, Eye, Nose, Throat

  • cough
  • rhinorrhea
  • lacrimation,

Gastrointestinal

  • GI irritation
  • diarrhea

Hematologic

  • bleeding

Interactions

May ↑ bleeding risk with antiplatelet agents or anticoagulants.May ↑ absorption of theophylline.May ↑ bleeding risk when taken with clove, garlic, ginger, ginseng, and ginkgo.
Oral (Adults) Powder—30–120 mg 3 times daily; Tincture—0.6–2 mL/dose; Oleoresin—0.6–2 mg/dose.
Topical (Adults) Apply cream 3 to 4 times daily (may take up to 14 days to see an effect).
Intranasal (Adults) 0.1 mL of a 10 mM suspension (300mcg/day) applied to nostril.

Availability

Powder:
Capsules:
Tincture:
Topical cream: 0.025% (Zostrix®), 0.075% (Zostrix-HP®), 0.1% (Capzacin-HP®)

Nursing implications

Nursing assessment

  • Assess pain intensity and location before and periodically during therapy.
  • Lab Test Considerations: Monitor: liver and kidney function tests in patients receiving oral therapy. Notes: Capsicum (or cayenne) alters temperature regulation and stimulates circulation.

Potential Nursing Diagnoses

Acute pain (Indications)

Implementation

  • Topical: Apply to affected area not more than 3–4 times daily. Avoid getting medication into eyes or on broken or irritated skin. Do not bandage tightly.
    • Topical lidocaine may be applied during the first 1–2 wk of treatment to reduce initial discomfort.

Patient/Family Teaching

  • Instruct patient on the correct method for application. Rub cream into affected area well so that little or no cream is left on the surface. Gloves should be worn during application or hands should be washed immediately after application. If application is to hands for arthritis, do not wash hands for at least 30 min after application.
  • Advise patient to apply missed doses as soon as possible unless almost time for next dose. Pain relief lasts only as long as capsaicin is used regularly.
  • Inform patient that transient burning may occur with application, especially if applied less than 3–4 times daily. Burning usually disappears after the first few days but may continue for 2–4 wks or longer. Burning is increased by heat, sweating, bathing in warm water, humidity and clothing. Burning usually decreases in frequency and intensity the longer capsaicin is used. Decreasing number of daily doses will not lessen burning but may decrease amount of pain relief and may prolong period of burning.
  • Caution patient to flush area with water if capsaicin gets into eyes and to wash with warm but not hot, soapy water if capsaicin gets on other sensitive areas of the body. A diluted vinegar solution can be used to remove capsicum cream (capsaicin is not water washable).
  • Instruct patients with herpes zoster (shingles) not to apply capsaicin cream until lesions have completely healed.
  • Advise patient to discontinue use and notify health care professional if pain persists longer than 1 mo, worsens, or if signs of infection occur.

Evaluation/Desired Outcomes

  • Decrease in discomfort associated with:.
    • postherpetic neuralgia.
    • disbetic neuropathy.
    • rheumatoid arthritis.
    • osteiarthritis.
  • Pain relief usually begins within 1–2 wks with arthritis, 2–4 wks with nauralgia, and 4–6 wks with neuralgias of the head and neck.
(1) A condiment used in certain cuisines, in particular Mexican, that is particular high in capsaicin
(2) Cayenne, see there, Capsicum frutescens
The intensity of the ‘sting’ of hot chillis is measured in Scoville units
References in periodicals archive ?
The chile pepper is not just a top crop in the Hatch Valley of southwest New Mexico, it is a key part of the regional culture.
The question was, could the Chile Pepper Institute establish the benchmark for chili heat?
We didn't want to make it too hot, because we wanted people to enjoy it and be able to taste the uniqueness of the Bhut Jolokia," says Paul Bosland, the Chile Pepper Institute's director and widely recognized as the world's foremost authority on chile peppers.
NOTE: Wear plastic gloves when handling chile peppers, and wash your hands thoroughly with soap and water before touching sensitive parts of your body, especially your face.
VJI chile peppers are available in juices and purees, in sauces, diced, and in blends that are designed to eliminate the need for chopping, juicing or dicing by food product manufacturers or foodservice personnel, making them the customer-friendly choice
Industry sources say imports account for 50% to 80% of the dried chile peppers sold in Mexico.
MISSISSIPPI SIX DIP 1 round loaf bread (savory, not sweet) 1 (8-ounce) package shredded cheddar cheese 1 (8-ounce) package cream cheese, softened 1 1/2 cups sour cream 1 (4-ounce) jar dried beef, chopped 1 small can chopped green chile peppers 1 bunch green onions, chopped Worcestershire sauce to taste
But uniquely Kalsec have utilised this system to carefully dehydrate Chile Peppers thereby developing a stream like process which has thoroughly dependable, consistent and controllable results.
She brings a dish with salt, limes, and tiny chile peppers.
He gets caught stealing chile peppers from a garden.
Last month's announcement of testing results by the CPI have put to rest a number of unsubstantiated assertions by people claiming to have created a "new species" of super-hot chile peppers.