norfloxacin

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norfloxacin

 [nor-flok´sah-sin]
a broad-spectrum quinolone antibacterial agent effective against penicillin-resistant gram-negative and gram-positive bacteria.

norfloxacin

/nor·flox·a·cin/ (nor-flok´sah-sin) a broad-spectrum antibacterial effective against a wide range of aerobic gram-negative and gram-positive organisms.

norfloxacin

(nôr-flŏk′sə-sĭn)
n.
An oral antibiotic, C20H24N5O4, of the fluoroquinolone class.

norfloxacin

[nôrflok′səsin]
an oral antibacterial drug.
indications It is prescribed for the treatment of bacterial urinary tract infections, sexually transmitted gonorrhea, and proctitis.
contraindications Hypersensitivity to quinolones or pregnancy or lactation prohibits its use. It should be used with caution in patients younger than 18 years because of arthropathy. Concomitant use of nitrofurantoin drugs is not recommended, and concomitant use of corticosteroids can increase the risk of arthropathy in the elderly.
adverse effects Typical side effects include nausea, dizziness, and headache. Severe hypersensitivity reactions, tendon rupture, and numerous other effects have been reported with relatively low incidence.

norfloxacin

Antibiotics A broad-spectrum–gram-negative bacilli, staphylococci–fluoroquinolone with limited activity against streptococci and anaerobes. See Fluoroquinolone.

norfloxacin

A quinolone antibacterial drug used to treat urinary tract infections. A brand name is Utinor.

antibiotic 

1. Pertaining to the ability to destroy or inhibit other living organisms.
2. A substance derived from a mould or bacterium, or produced synthetically, that destroys (bactericidal) or inhibits the growth (bacteriostatic) of other microorganisms and is thus used to treat infections. Some substances have a narrow spectrum of activity whereas others act against a wide range of both gram-positive and gram-negative organisms (broad-spectrum antibiotics). Antibiotics can be classified into several groups according to their mode of action on or within bacteria: (1) Drugs inhibiting bacterial cell wall synthesis, such as bacitracin, vancomycin and the β-lactams based agents (e.g. penicillin, cephalosporins (e.g. ceftazidime, ceftriaxone, cefuroxime). (2) Drugs affecting the bacterial cytoplasmic membrane, such as polymyxin B sulfate and gramicidin. (3) Drugs inhibiting bacterial protein synthesis, such as aminoglycosides (e.g. amikacin sulfate, framycetin sulfate, gentamicin, neomycin sulfate and tobramycin), tetracyclines, macrolides (e.g. erythromycin and azithromycin) and chloramphenicol. (4) Drugs inhibiting the intermediate metabolism of bacteria, such as sulfonamides (e.g. sulfacetamide sodium) and trimethoprim. (5) Drugs inhibiting bacterial DNA synthesis, such as nalixidic acid and fluoroquinolones (e.g. ciprofloxacin, levofloxacin, moxifloxacin, norfloxacin and ofloxacin). (6) Other antibiotics such as fusidic acid, the diamidines, such as propamidine isethionate and dibrompropamidine. Syn. antibacterial. See antiinflammatory drug; fusidic acid.

norfloxacin (nôrflok´səsēn),

n brand name: Noroxin;
drug class: fluoroquinolone antiinfective;
action: a broad-spectrum bactericidal agent that inhibits the enzyme DNA gyrase needed for replication of DNA;
uses: adult urinary tract infections.

norfloxacin

a fluoroquinolone antibiotic, used particularly in urinary tract infection.