chenodeoxycholic acid

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chenodeoxycholic acid

 [ke″no-de-ok″se-ko´lic]
one of the primary bile acids in humans, usually found conjugated with glycine or taurine; it facilitates fat absorption and cholesterol excretion. The pharmaceutical preparation, called chenodiol, is used in treatment of gallstones.

che·no·de·ox·y·cho·lic ac·id

(kē'nō-dē-oks'ē-kō'lik as'id),
A major bile acid in many vertebrates, usually conjugated with glycine or taurine; it facilitates cholesterol excretion and fat absorption; administered to dissolve cholesterol gallstones.
Synonym(s): chenodiol

chenodeoxycholic acid

/che·no·de·oxy·cho·lic ac·id/ (ke″no-de-ok″se-kol´ik) a primary bile acid, usually conjugated with glycine or taurine; it facilitates fat absorption and cholesterol excretion.

chenodeoxycholic acid

[kē′nōdē·ok′sikō′lik]
a secondary bile acid. It is used in vivo to dissolve cholesterol gallstones, particularly in the elderly and poor-risk patients. See also ursodeoxycholic acid.

chenodeoxycholic acid

A bile acid with detergent properties. It has been used as a drug to dissolve GALLSTONES, but this takes 6 months to 2 years.

che·no·de·ox·y·cho·lic ac·id

(kē'nō-dē-oks'ē-kō'lik as'id)
A major bile acid in many vertebrates; facilitates cholesterol excretion and fat absorption; administered to dissolve cholesterol gallstones.

chenodeoxycholic acid

a primary bile acid, C24H40O4, administered as an anticholelithogenic agent. Called also chenodiol.
References in periodicals archive ?
Bile acid binding resins are well known to reduce serum cholesterol by reducing the enterohepatic recirculation of bile acids, upregulating the LDL receptor, and stimulating the increased conversion of cholesterol to the bile acids, cholate and chenodeoxycholate, by upregulating the expression of 7 [alpha]-hydroxylase.
If it can be established that an increase in fiber-rich foods could, throughout life, maintain an adequate production of chenodeoxycholate and reduce or even prevent the formation of gallstones, then recommending dietary changes would certainly be a better approach than having to remove gallstones surgically or dissolve them with medicines after they have already develop.