chemotaxis

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Related to Chemotactic factors: histamine, chemotaxin

chemotaxis

 [ke″mo-tak´sis]
list; movement (taxis) in response to the influence of chemical stimulation. adj., adj chemotac´tic.
leukocyte chemotaxis the response of leukocytes to products formed in immunologic reactions, wherein leukocytes are attracted to and accumulate at the site of the reaction; a part of the inflammatory response. See also inflammation.

che·mo·tax·is

, positive chemotaxisnegative chemotaxis (kē'mo-tak'sis),
1. Movement of cells or organisms in response to chemicals, whereby the cells are attracted (positive chemotaxis) or repelled (negative chemotaxis) by substances exhibiting chemical properties.
2. The migration of polymorphonuclear leukocytes and macrophages toward higher concentrations of certain fragments of complement.
[chemo- + G. taxis, orderly arrangement]

chemotaxis

/che·mo·tax·is/ (-tak´sis) taxis in response to the influence of chemical stimulation.chemotac´tic

chemotaxis

(kē′mō-tăk′sĭs, kĕm′ō-)
n.
The characteristic movement or orientation of an organism or cell along a chemical concentration gradient either toward or away from the chemical stimulus.

che′mo·tac′tic (-tăk′tĭk) adj.
che′mo·tac′ti·cal·ly adv.

chemotaxis

[-tak′sis]
Etymology: Gk, chemeia + taxis, arrangement
movement toward or away from a chemical stimulus. Chemotaxis is a cellular function, particularly of neutrophils and monocytes, whose phagocytic activity is influenced by chemical factors released by invading microorganisms.

che·mo·tax·is

, positive chemotaxis , negative chemotaxis (kē'mō-tak'sis, pozi-tiv, negă-tiv)
Movement of cells or organisms in response to chemicals.
Synonym(s): chemotropism.

chemotaxis

The movement of a cell or other living organism in a particular direction as a result of attraction by an increasing concentration of a chemical substance. Cells of the immune system find their prey by this means.

chemotaxis

the orientation of a motile cell or an organism in relation to the presence of a particular chemical, the response to a chemorepellent being negative (moving away) and to a chemoattractant being positive (moving towards). For example, the movement of a wasp towards an attractive odour such as beer would be positive chemotaxis. Cells are able to detect changes in the concentration of the chemical and alter their mobility accordingly For example, bacteria will change their pattern of swimming and tumbling.

chemotaxis

attraction of inflammatory cells (neutrophils, macrophages) to sites of actual or potential tissue trauma, mediated by the local release of trigger chemicals (exogenous substances [from infecting microorganisms] and endogenous acute inflammatory response compounds [complement factors, clotting factors, histamine, kinins, prostaglandins, leukotrienes, cytokines, and platelet-activating factor])

che·mo·tax·is

, positive chemotaxis , negative chemotaxis (kē'mō-tak'sis, pozi-tiv, negă-tiv)
Movement of cells in response to chemicals, whereby the cells are attracted or repelled by substances exhibiting chemical properties.

chemotaxis (kē´mōtak´sis),

n a response involving movement that is positive (toward) or negative (away from) to a chemical stimulus.
chemotaxis, leukocyte,
n the phagocytic activity of neutrophils and monocytes in response to chemical factors released by invading microorganisms.

chemotaxis

taxis or directional movement in response to the influence of chemical stimulation.

leukocyte chemotaxis
the response of leukocytes to products formed in immunological reactions, wherein leukocytes are attracted to and accumulate at the site of the reaction; a part of the inflammatory response. See also inflammation.
References in periodicals archive ?
The production of chemotactic factors and specific adhesion molecules in the mammary gland allows the cells of mucosal origin to enter the mammary gland from the circulation and increase the production of immunologically active proteins in situ.
Some of the mediators are histamine, heparin, leukotrienes, serotonin, chemotactic factors, tryptase, chymase and prostaglandins.
Zymosan is well known as a powerful releaser of arachidonic acid metabolites, which are very important for vasodilation and swelling as well as the release of chemotactic factors that recruit polymorphonuclear cells to the affected zone and that contribute actively to the early phase of inflammatory reaction (Remirez et al.
When immune complexes are formed, some immunoglobulin isotypes can fix complement by the classical pathway, and the induction of an unimpeded cascade of local complement activation leads to the production of chemotactic factors, such as C5a, which attract the leukocytes that further hasten downstream tissue destructive activities.
6) In rabbits, Hashimoto et al showed that steroids suppress the formation of granulation tissue (1) by reducing vascular permeability, (2) by decreasing extravasation and the migration of inflammatory cells to the site of infection, (3) by inhibiting the production of a variety of chemotactic factors (especially complement factors and lymphocyte-derived factors), and (4) by acting on growth factors such as vascular endothelial growth factor and transforming growth factor beta.
The consequent activation of the complement system causes release of chemotactic factors, attracting polymorphonuclear leukocytes into the wall of arteries that, in turn, release proteolytic enzymes, resulting in vascular necrosis.
The hypothesis behind it was that the blood would clot, which will in turn provide a provisional matrix of fibrin, fibronectin, von Willebrand factor, and thrombospondin (19,20,21), which facilitates the early migration of cells into the wound environment, (22) stimulates fibroblast proliferation (via thrombin), and shield mitogenic and chemotactic factors from inhibitors.
The stimulated macrophages secrete chemotactic factors such as lymphokines, which then attract T-helper (T4) lymphocytes.
1991), which being the active chemotactic factors cause increased permeability (Robertson RP, 1987).
Not only does this anaerobic bacterium produce lipases, proteases, and other extracellular enzymes, it also secretes chemotactic factors attracting polymorphonuclear leukocytes, lymphocytes, and macrophages.
These organisms produce neutrophil chemotactic factors, which attract neutrophils to release inflammatory mediators such as reactive oxygen species (ROS) and lysosomal enzymes, resulting in disruption of the integrity of the follicular epithelium (Webster and Leyden, 1980).
As mentioned, the complement cascade activates autoantibodies and chemotactic factors, which leads to cell degranulation.