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chemoreceptor trigger zone

   Also found in: Acronyms, Wikipedia 0.02 sec.
chemoreceptor trigger zone
Area postrema Neuroanatomy The neural center for emesis, located in the floor of the 4th ventricle, which receives vagal afferents or stimulated directly by apomorphine, cardiac glycosides, ergot compounds, chemotherapeutics, staphylococcal enterotoxin, salicylate and nicotine and other circulating chemicals; in contrast to the adjacent but distinct vomiting center, the CTZ does not respond to electrical stimulation


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1) The facts that stimulation of the area postrema produces vomiting in cats and that it is not protected by the blood-brain barrier suggest that the area postrema contains the chemoreceptor trigger zone for the production of vomiting in response to noxious chemicals.
Labyrinth stimulation activates the chemoreceptor trigger zone and can lead to emesis.
 
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