We also reported that tumor growth and metastasis may be stimulated by tumor-induced angiogenesis and lymphangiogenesis through increases in TAMs at the tumor site and blood monocyte chemoattractant
protein-1 (MCP-1) (Kimura and Sumiyoshi 2013).
Enhancement of growth in juvenile freshwater prawns, Macrobrachium rosenbergii, through the use of a chemoattractant
Monocytes chemotactic and activating factor/monocyte chemoattractant
protein-1-mediated histamine release from human nasal mucosa.
These cells express receptors for inflammatory chemokines and chemoattractants
that are released during infections.
protein-1 regulates migration and infiltration of monocytes into tissues where they replenish infection-fighting macrophages.
The selective egress of leukocyte subpopulations from the circulation is determined by (i) the type of chemoattractant
presented by vascular endothelial cells; and (ii) differential utilisation of adhesion molecules.
These rectifications in receptor-ligand level were reflected in improved CCR5 dependent, p38MAP kinase mediated migration of MO/Mo after NLGP treatment against a standard chemoattractant
Sano H, Hsu DK, Yu L, Apgar JR, Kuwabara I, Yamanaka T, et al: Human galectin-3 is a novel chemoattractant
for monocytes and macrophages.
The work is focused on the monocyte chemoattractant
protein 1 (MCP-1 or CCL2) which plays a major role in atherosclerosis - a condition in which artery walls thicken as the result of a build-up of fatty materials such as cholesterol and is more commonly known as 'furring of the arteries' which can cause severe heart disease, and can prove fatal.
It is a chemoattractant
for circulating monocytes (Quinn et al, 1987).
Chemotaxis, the movement of cells toward a concentration gradient of chemoattractant
, was first discovered as a sperm guidance mechanism in marine species (8).
discoideum; methods for measuring spatiotemporal dynamics of chemoattractant
concentrations, activation of receptors, heterotrimeric G-proteins, small G-protein Ras signaling, and actin cytoskeleton assembly using different imaging techniques; and the use of computer-based quantitative models for addressing the complexity of a signaling network.