Modulation of multidrug resistance in cancer cells by chelidonine and Chelidonium majus alkaloids.
Proapoptotic activity of Ukrain is based on Chelidonium majus L.
Antispasmodic and relaxant activity of chelidonine, protopine, coptisine, and Chelidonium majus extracts on isolated guinea-pig ileum.
Alkaloids from Chelidonium majus
and their inhibitory effects on LPSinduced NO production in RAW264.
2 ml in the right thigh once, (3) Irradiated group (R): animals were exposed to 6 Gy gamma radiation as a single shot at 17th day post EAC inoculation, (4): Chelidonium majus
ethanolic extract treated group (CM): animals that received 100mg/kg b.
In this study the cytotoxic effects of two Chelidonium majus L.
Ukrain(TM), a semisynthetic chelidonium majus alkaloid derivative, acts by inhibition of tubulin polymerization in normal and malignant cell lines.
Chemical analyses of Ukrain, a semi-synthetic chelidonium majus alkaloid derivative, fail to confirm its trimeric structure.
Proapoptotic activity of Ukrain is based on Chelidonium majus L alkaloids and mediated via a mitochondrial death pathway.
Potential preventive effects of Chelidonium majus L (Papaveraceae) herb extract on glandular stomach tumor development in rats treated with N-methyl-N'-nitro-N nitrosoguanidine (MNNG) and hypertonic sodium chloride.
50] could not be determined for Atropa belladonna, Plantago major and Chelidonium majus as their extracts did not elicit 50% inhibition (Fig.
50] tested ([mu]g/ml) + Psoralea corylifolia (2) Fruit 22 [+ or -] 6 (Leguminosae) Dianthus sinensis (1) Whole plant 111 [+ or -] 19 (Caryophyllaceae) Phytolacca polyandra (1) Whole plant 129 [+ or -] 13 (Phytolaccaceae) Sophora flavescens Ait (2) Root 134 [+ or -] 17 (Leguminosae) Cephalotaxus fortunei (2) Branch 134 [+ or -] 27 (Cephalotaxaceae) Polygonatum odoratum (1) Root 142 [+ or -] 11 (Convallariaceae) Coptis chinensis French (2) Whole plant 412 [+ or -] 32 (Ranunculaceae) Terminalia chebula Retz (2) Fruit 201 [+ or -] 51 (Combretaceae) Atropa belladonna (1) Fruit N/D (Solanaceae) Chelidonium majus (1) Whole plant N/D (Papaveraceae) Plantago major (1) Root N/D (Plantaginaceae) Plants orginated from: (1)National Botanic Gardens, Glasnevin, Dublin (2)Taiwan.