CASTLE

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CASTLE

(kas'ĕl),
Acronym for carcinoma sharing thymuslike elements.

Cas·tle

(kas'ĕl),
William B., U.S. physician, 1897-1991. See: Castle intrinsic factor.

CASTLE

Cardiology
Candesartan Amlodipine Study of Tolerability and Efficacy.
 
Pathology
Carcinoma showing thymus-like elements. An acronym for a rare indolent tumour that occurs in middle-aged adults. CASTLE is similar to thymic carcinoma of the lymphoepithelioma or squamous cell variety, and thought to arise either from ectopic thymus or remnants of branchial pouches that retain the potential to differentiate along the thymic lines.

Sites
Anterior mediastinum, soft tissues of the neck and thyroid; it ranges from completely benign to malignant.

Prognosis
Rarely metastasises.

CASTLE

Cardiology A clinical trial–Candesartan Amlodipine Study of Tolerability & Efficacy