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Charcot-Leyden crystal

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Charcot-Leyden crystal
[shärkō′lī′dən]
Etymology: Jean M. Charcot; Ernst V. von Leyden, German physician, 1832-1910
any of the proteinaceous crystalline structures shaped like narrow, double pyramids found in the sputum of persons suffering from asthma and found in the feces of dysentery patients. Charcot-Leyden crystals occur in association with the fragmentation of eosinophils. Also called asthma crystal, leukocytic crystal.


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5) They described this a s allergic mucin, which consisted of degenerating eosinophils, desquamated respiratory epithelial cells, and Charcot-Leyden crystals.
6) Charcot-Leyden crystals are composed of the enzyme lysophospholipase (also referred to as Charcot-Leyden crystal protein), which is present in the granules of eosinophils and basophils.
Crystal structure of human Charcot-Leyden crystal protein, an eosinophil lysophospholipase, identifies it as a new member of the carbohydrate-binding family of galectins.
 
 
 
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