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Chaperone
(redirected from Chaperone proteins)

   Also found in: Dictionary/thesaurus, Legal, Wikipedia 0.01 sec.
chaperone /chap·er·one/ (shap´er-ōn) someone or something that accompanies and oversees another.
molecular chaperone  any of a diverse group of proteins that oversee the correct intracellular folding and assembly of polypeptides without being components of the final structure.

Chaperone
Any of a class of cytoplasmic proteins found in both prokaryotes and eukaryotes, which facilitate the correct assembly or disassembly of newly synthesized oligomeric protein complexes, participating in transmembrane targeting and protein folding

chaperone
a family of proteins that aid in the folding of target proteins.


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The presence of mutant proteins in the nucleus may cause a stress response with increased levels of protective chaperone proteins.
MaCRA has enabled CytRx to rapidly and quantifiably screen large numbers of small molecule compounds to identify potential drug candidates that modify the activity of a protein known as heat shock transcription factor 1 (Hsf1) and consequently control entire groups of molecular chaperone proteins that repair or degrade toxic misfolded proteins present in diseased cells.
Hsf-1 is thought to be a master regulator that controls the amount of an entire family of molecular chaperone proteins that repair or degrade toxic misfolded proteins present in diseased cells.
 
 
 
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