CFTR(redirected from Channel conductance-controlling ATPase)
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CFTRA gene on chromosome 7q31.2 that encodes cystic fibrosis transmembrane conductance regulator, a protein of the MRP subfamily of the superfamily of ATP-binding cassette (ABC) transporters, which transport various molecules across extra- and intracellular membranes and many of which are involved in multidrug resistance. CFTR functions as a chloride channel and controls the regulation of other transport pathways.
CFTR mutations cause cystic fibrosis and bilateral aplasia of the vas deferens.
Abbreviation for cystic fibrosis transmembrane regulator.