chalone

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chalone

 [kal´ōn]
a group of tissue-specific, water-soluble substances that are produced within a tissue and that inhibit mitosis of the cells of that tissue and whose action is reversible.

cha·lone

(kā'lōn),
Originally, a hormone (for example, enterogastrone) that inhibits rather than stimulates; now, mitotic inhibitor (often glycoproteins) elaborated by a tissue and active only on that type of tissue, regardless of species; thus, a reversible tissue-specific mitotic inhibitor.
[G. + chalaō, to relax, + -one]

chalone

/chal·one/ (kal´ōn) a group of tissue-specific water-soluble substances that are produced within a tissue and that inhibit mitosis of cells of that tissue and whose action is reversible.

chalone

(kā′lōn′, kăl′ōn′)
n.
Any of several polypeptides that cause the reversible inhibition of mitosis in the cells that secrete them.

chalone

[kā′lōn]
Etymology: Gk, chalan, to relax
any one of numerous polypeptide inhibitors that are elaborated by a tissue and function like hormones on specific target organs.

cha·lone

(kal'ōn)
Any of a number of mitotic inhibitors elaborated by a tissue and active only on that type of tissue, regardless of species; a reversible tissue-specific mitotic inhibitor.
[G. + chalaō, to relax, + -one]

chalone

one of a group of chemicals (PEPTIDES and GLYCOPROTEINS) occurring in living animal tissues which specifically inhibit MITOSIS.

chalone

a group of tissue-specific, water-soluble substances that are produced within a tissue and that inhibit mitosis of the cells of that tissue and whose action is reversible.
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