challenge

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challenge

 [chal´enj]
1. to administer a chemical substance to a patient for observation of whether the normal physiological response occurs.
2. in immunology, to administer antigen to evoke an immunologic response in a previously sensitized individual.
3. the administration of such a substance in order to assess for a response; called also provocation.
bronchial challenge (inhalational challenge) bronchial challenge test.

challenge

/chal·lenge/ (chal´enj)
1. to administer a substance to monitor for the normal physiological response.
2. in immunology, to administer an antigen to monitor the response in a sensitized person.

challenge

(chăl′ənj)
n.
Immunology The induction or evaluation of an immune response in an organism by administration of a specific antigen to which it has been sensitized.
v. chal·lenged, chal·lenging, chal·lenges
v.tr.
Immunology To induce or evaluate an immune response in (an organism) by administering a specific antigen to which it has been sensitized.

chal′lenge·a·ble adj.

challenge

1 a method of testing the sensitivity of an individual to a hormone, allergen, or other substance by administering a sample. A small amount may be injected to determine whether the immune system will react by producing appropriate antibodies.
2 a term used to describe the rapid or concentrated infusion of a substance such as potassium or magnesium in the face of a life-threatening deficiency or a rapid infusion of IV fluid to differentiate between fluid deficit or renal failure as the cause of severely decreased urine output.

challenge

Immunology The administration of an antigen or allergen to a person who has been previously exposed to the antigen, specifically to evoke an immune response

challenge,

n a stimulating or de-manding circumstance. To develop effective problem-solving skills and strategies, it is necessary to perceive such circumstance as inconvenience or burden instead of overwhelming impediments.
References in periodicals archive ?
Given the woeful values attached to media groups at present, the owner of Bravo, Challenge TV and Living TV had more value as part of a company combining production and distribution, Mr Burdick said.
In the programme, Endurance UK on Challenge TV, contestants square up to see who can survive a shocking series of trials, including:
But the lanky TV star, who has twice been treated for alcoholism, stunned guests during the Challenge TV Game Show Awards at the Savoy Hotel by humiliating host Bob Monkhouse and lying flat on the floor for photographers.
Ultimate Poker Challenge TV Show -- Copyright and trademark infringement for use of WPTE footage and for superimposing the Ultimate Poker Challenge mark over the WORLD POKER TOUR mark.
She worked for the Disney Channel, became the face of the National Lottery Daily Play on Challenge TV, hosted the EuroMillions draw and found time to do a Met Office meteorology course.
Most Saturdays I find myself plonked on the sofa, contentedly enjoying a re-run of Big Break on Challenge TV.
In 1997 he was fronting quiz Winner Takes All for Challenge TV.
55pm every Friday on Challenge TV (Sky Channel 124, NTL Channel 152), visit www.
Affiliates of the Winner Channel have included Flextech TV and its channels Challenge TV and Bravo, and Channel 4.
Other stars were out in Cardiff this week to film the Challenge TV show included glamour girl Lindsay Dawn Mackenzie, ex-Barings Bank employee Nick Leeson, snooker pundit Willie Thorne, legendary drugs smuggler Howard Marks and Radio One's Colin Murray.
The images were broadcast during adventure programme Fort Boyard by game show channel Challenge TV.
Two Way and Pearson have also finalised a deal with Flextech Television to produce interactive versions of re-runs of game shows Family Fortunes, 100%, and Strike It Lucky on Challenge TV.

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