Chagas disease

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South A·mer·i·can try·pan·o·so·mi·a·sis

trypanosomiasis caused by Trypanosoma (or Schizotrypanum) cruzi and transmitted by certain species of reduviid (triatomine) bugs. In its acute form, it is seen most frequently in young children, with swelling of the skin at the site of entry, most often the face, and regional lymph node enlargement; in its chronic form it can assume several aspects, commonly cardiomyopathy, but megacolon and megaesophagus also occur; natural reservoirs include dogs, armadillos, rodents, and other domestic, domiciliated, and wild mammals.

South A·mer·i·can try·pan·o·so·mi·a·sis

(sowth ă-mer'i-kăn trī-pan'ō-sŏ-mī'ă-sis)
Disease caused by Trypanosoma (or Schizotrypanum) cruzi and transmitted by some species of reduviid (triatomine) bugs. In its acute form, it is seen most frequently in young children, with swelling of the skin at the site of entry, most often the face, and regional lymph node enlargement; in its chronic form it can assume several aspects, commonly cardiomyopathy, but megacolon and megaesophagus also occur; natural reservoirs include domestic, domiciliated, and wild mammals.
Synonym(s): Chagas disease, Chagas-Cruz disease, Cruz trypanosomiasis.

Chagas disease

(shag'as)
[Carlos Ribeiro Justiniano Chagas, Brazilian physician, 1879–1934]
A bloodborne disease caused by Trypanosoma cruzi and transmitted by the biting of a reduviid bug. It is characterized by fever, lymphadenopathy, hepatosplenomegaly, and facial edema. Chronic cases may be mild or asymptomatic, or may be accompanied by myocarditis, cardiomyopathy, megaesophagus, megacolon, or death.

Etiology

Chagas disease may be transmitted from person-to-person by needlestick injury, transfusion, organ donation, or during childbirth.

Synonym: American trypanosomiasis; South American trypanosomiasis See: Trypanosoma cruzi

Chagas,

Carlos J.R., Brazilian physician and parasitologist, 1879-1934.
Chagas disease - parasitic infection transmitted by certain species of reduviid (triatomine) bugs. Synonym(s): Chagas-Cruz disease; Chagas-Mazza disease; Cruz trypanosomiasis; South American trypanosomiasis
Chagas-Cruz disease - Synonym(s): Chagas disease
Chagas-Mazza disease - Synonym(s): Chagas disease

Mazza,

Salvador, Argentinian physician, 1886-1946.
Chagas-Mazza disease - Synonym(s): Chagas disease
References in periodicals archive ?
Furthermore, patients with known Chagas cardiomyopathy and/or megacolon who were hospitalized for routine checks or for elective pacemaker implantation or colon surgery were also enrolled in groups CM and M.
These included 1 case of acute Chagas myocarditis (ACM), 4 cases of chronic Chagas cardiomyopathy (CCC), and 4 cases of indeterminate chronic Chagas (ICC) (asymptomatic patients seropositive for Typanosoma cruzi) (1).
GlobalData's clinical trial report, Chagas Cardiomyopathy Global Clinical Trials Review, H1, 2012" provides data on the Chagas Cardiomyopathy clinical trial scenario.
Three patients with negative serologic findings and positive PCR results had clinical signs and symptoms that suggested Chagas cardiomyopathy.