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ceroid

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ceroid
[sir′oid]
Etymology: L, cera, wax; Gk, eidos, form
a golden, waxy pigment appearing in the cirrhotic livers of some individuals, in the GI tract, in the nervous system, and in the muscles. It is an insoluble, acid-fast, sudanophilic pigment.

ceroid
an insoluble polymer of oxidized lipid and protein; an acid-fast, sudanophilic, pigment found in the liver, the nervous system and muscle. See also ceroid lipofuscinosis.

ceroid
A complex of alcohol-insoluble, oxidized polyunsaturated lipid pigment(s) resulting from the peroxidation of unsaturated lipids that are similar or identical to lipofuscin; ceroid accumulates in macrophages of the heart, liver, GI tract, and brain in the elderly and is thus termed 'wear and tear' pigment; it has been inculpated in age-related organ dysfunction–see 'garbage can' hypothesis, hypovitaminosis E, cathartic colon, and hereditary conditions–eg, Batten's disease, sea-blue histiocytosis


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McGlynn plans to report on the progress of the Company's ongoing Phase 1 clinical trial in neuronal ceroid lipofuscinosis, plans for expanding the company's Neural Program to additional indications, and an update on the company's Liver Program, including a new initiative to develop a cell-based therapy for liver diseases.
About Neuronal Ceroid Lipofuscinosis (Batten Disease)
About Neuronal Ceroid Lipofuscinosis (Batten Disease)
 
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