central dogma of molecular biology

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central dogma of molecular biology

The outdated principle which states that proteins are made from RNA, which in turn is made from DNA. Other permutations are found in nature; e.g., RNA viruses use a reverse transcriptase to make complementary DNA.
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Genetic loophole The occasional switch of a chemical unit in RNA to a slightly different form can cause a cell's protein-building machinery to roll right through a molecular stop sign, a find that violates the central dogma of genetics (SN: 7/16/11, p.
The central dogma of genetics holds that double-stranded DNA makes single-stranded messenger RNA, which in turn makes protein.

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