For example, cytokines stimulate collagen synthesis in smooth muscle cells and promote endothelial and vascular smooth muscle cell activation through the induction of cellular adhesion molecules
Association of circulating cellular adhesion molecules
with menopausal status and hormone replacement therapy: time-dependent change in transdermal, but not oral estrogen users.
Cytokine-induced expression of cellular adhesion molecules
was measured on primary human coronary artery endothelial cell (HCAEC) cultures.
Intercellular adhesion molecule-1 (ICAM-1) and E-, P-, and L-selectin are cellular adhesion molecules
involved in the recruitment of leukocytes on the activated vessel wall during inflammation (1) and play an important role in the early stages of atherosclerosis and its complications (2).
The new research, she says, "has the implication that other cellular adhesion molecules
may well be major receptors for other, much more pathogenic viruses.
ICAM-1 is part of a molecular family (known as Cellular Adhesion Molecules
, or CAMs) that can be found on the surface of virtually every cell in the body, including cells that line the inflamed gastrointestinal (GI) tract.
The effects of acute psychological stress on cellular adhesion molecules
ICAM-1 is part of a family of molecules, the cellular adhesion molecules
, that can be found on the surface of virtually every cell in the body, including cells that line the colon.
PS-341 has been shown to inhibit cell growth signaling pathways, induce apoptosis, and inhibit the expression of cellular adhesion molecules
Scientists have discovered all sorts of developmental proteins, cellular adhesion molecules
, growth factors and glial cells that actually support growth and play an active role in function," Ron Cohen, M.
Using a rational drug design approach, TRL's scientists are discovering new chemical compounds which inhibit specific cellular adhesion molecules
involved in inflammation- related disorders.
The research collaboration will focus on the discovery and design of synthetic compounds that inhibit the interaction of cellular adhesion molecules
(CAMs), such as selectins and integrins.