KRT18

(redirected from Cell proliferation-inducing gene 46 protein)

KRT18

A gene on chromosome 17q21.2 that encodes a type-I keratin, an intermediate filament protein. Together with its filament partner keratin 8, they are the most commonly expressed of all intermediate filaments, and found in tissues lined by single layer epithelia.
 
Molecular pathology
KRT18 mutations are associated with cryptogenic cirrhosis.