SERPINF1

(redirected from Cell proliferation-inducing gene 35 protein)

SERPINF1

A gene on chromosome 17p13.3 that encodes a member of the serine protease inhibitor (serpin) family. SERPINF1 does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins; it has no serine protease inhibitory activity, but it inhibits angiogenesis and is a neurotrophic factor involved in neuronal differentiation in retinoblastoma cells.
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