CDK6

(redirected from Cell division protein kinase 6)

CDK6

A gene on chromosome 7q21-q22 that encodes a cyclin-dependent kinase, which is a catalytic subunit of the protein kinase complex important in cell cycle G1-phase progression and G1/S transition. CDK6, with CDK4, phosphorylates and regulates the activity of tumour suppressor protein Rb.

Molecular pathology
CDK6 expression is upregulated in some cancers.
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