Immunophenotypic analysis revealed positive expression of Cytokeratin (CK) 20 and CDX2
which was compatible with appendiceal primary and ovarian metastases.
The protocol is designed to mimic natural embryonic development, and CDX2
is a molecular marker found in gut tissues.
Mouse anti-human cdx2
clone, Ready for use; Polycl.
39) In addition, the malignancy may show an enteric immunophenotype with at least focal positivity for CDX2
Immunohistochemistry staining of the tumor for CK7, CK20, and CDX2
can also be employed to help make this determination.
91) Thus, as expected, expression of Cdx2
was significantly higher in human gastric cancer mucosa than in non-cancerous mucosa.
in tumour cells and negativity for PSA, AMACR, and CDX2
in paraffin section helped in identifying the tumour as primary in the urinary bladder.
Immunohistochemistry showed tumor positivity for vimentin, smooth-muscle actin and synaptophysin and negativity for the keratin 7, keratin AE1/AE3, keratin 20, keratin 5/6, chromogranin, KIT (CD117), CD34, CDX2
, CD56, protein-S100, p63 and desmin antigens (Figures 5 and 6).
VDR Polymorphism and Colorectal Cancer,"Cancer Epidemiol.
pylori] inhibits the expression of SOX2 in gastric epithelial cells, hence activating transcription factor CDX2
as a counterpart to MUC5AC gene inhibition andMUC2 gene induction," elaborated Dr.
Re-activate a colon tumor suppressor gene, CDX2
, which is deactivated early in the process of colon carcinogenesis.
Kannagi, "Transcription factors c-Myc and CDX2
mediate E-selectin ligand expression in colon cancer cells undergoing EGF/bFGF-induced epithelial-mesenchymal transition," Proceedings of the National Academy of Sciences of the United States of America, vol.