Cdk


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CDK

abbreviation for cyclin-dependent kinase.

kinase

(kin'as)
An enzyme that catalyzes the conversion of a proenzyme to a fully active enzyme.

cyclin-dependent kinase

Abbreviation: CDK
A family of enzymes involved in regulation of the cell cycle. They serve as targets for pharmacological manipulation of this cycle, particularly during the unregulated proliferation of tumor cells.

myosin light chain kinase

An enzyme in smooth muscle cells that catalyzes the transfer of a phosphate group from adenosine triphosphate to myosin, which initiates contraction.

protein kinase

See: protein kinase

tyrosine kinase

Any of a group of enzymes that influence signaling between cells, esp. as relates to cell growth and death, cellular adhesion and movement, and cellular differentiation. Abnormalities in tyrosine kinases are found in some human diseases, including chronic myeloid (myelogenous) leukemia.

cyclin-dependent kinase

Abbreviation: CDK
A family of enzymes involved in regulation of the cell cycle. They serve as targets for pharmacological manipulation of this cycle, particularly during the unregulated proliferation of tumor cells.
See also: kinase

Cdk

cyclin-dependent protein kinase.
References in periodicals archive ?
Co-crystal structure solution of initial candidates docked in the active site of the CDK enzyme guided parallel synthesis iterations that resulted in analogues with high CDK selectivity, nanomolar potency in cells and profound cell cycle effects.
The company continues to implement direct integrations with all other DMS applications that provide modern programmatic access like APIs or certification-driven integration like CDK 3PA.
Alterations in CDK activity have been associated in the development of viral infections, neurodegenerative disorders such as Alzheimers disease and proliferative diseases such as renal diseases and cancers.
The contract covers dialysis cannula, customized dialystvEnttset, kEnrlkateterlENs CDK, CDK catheter, tubing set, hose clamp, dialysis filters, dialysis equipment, dialysis concentrate, sterile filters, salt tablets for water softening, particle filters, disinfectant for water treatment plant etc.
CDK founding partner & prominent Dallas Employment Lawyer Keith Clouse notes, "In the six years since we formed the firm, CDK partners have been named to the Super Lawyers list each year.
0 of the Curl Rich Internet Application (RIA) Platform, the CDK library facilitates building data-centric applications in Curl and provides support for local SQL databases.
Online since 1995, CDK offers tens of thousands of recipes in a user-friendly, attractive format--all of which are free for visitors.
NASDAQ: FTNT), CyberArk Software Ltd (NASDAQ: CYBR), and CDK Global Inc.
Dozer is the co-founder and a managing partner of CDK Partners, a real estate development and investment company.